SCHEMBL30489495

SCHEMBL30489495

CC(C)(C)OC(=O)N1CCc2[nH]c3cccc(Oc4ccc(F)cc4)c3c2CC1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S1PR2 O95136 1/20 0.42
BAZ2B Q9UIF8 1/20 0.41
TRPV1 Q8NER1 2/20 0.40
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
PARP1 P09874 2/20 0.39
F12 P00748 2/20 0.39
BRD3 Q15059 1/20 0.39
HPGDS O60760 1/20 0.39
KDM4E B2RXH2 1/20 0.39
ALDH1A1 P00352 1/20 0.39
MAPT P10636 1/20 0.39
ALOX15 P16050 1/20 0.39
TSHR P16473 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
HSD17B10 Q99714 1/20 0.39
TNKS2 Q9H2K2 1/20 0.39
PARP2 Q9UGN5 1/20 0.39
GRM5 P41594 1/20 0.39
GRM1 Q13255 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30489496 0.81 S1PR2 (0.46) S1PR2BAZ2BTRPV1MEN1KMT2A
SCHEMBL25634079 0.81 CHRNA7 (0.42) BAZ2BMEN1KMT2AKDM4EALOX15
SCHEMBL6475935 0.80 PARP1 (0.43) BAZ2BTRPV1PARP1F12MAPT
SCHEMBL6482451 0.80 PARP1 (0.44) BAZ2BTRPV1PARP1F12MAPT
SCHEMBL25425099 0.80 PRMT5 (0.43) MEN1KMT2ACDK9
SCHEMBL30489504 0.78 S1PR2 (0.42) S1PR2MEN1KMT2APARP1HPGDS
SCHEMBL21114784 0.77 CTSK (0.48) BAZ2BTRPV1PARP1F12MAPT
SCHEMBL21588265 0.77 PARP1 (0.49) TRPV1PARP1F12TNKS2PARP2
SCHEMBL29357232 0.77 CTSK (0.48) BAZ2BTRPV1PARP1F12MAPT
SCHEMBL6481176 0.77 PARP1 (0.45) BAZ2BTRPV1PARP1F12MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250235463-A1 PHENOXY AND BENZYLOXY SUBSTITUTED PSYCHOPLASTOGENS AND USES THEREOF DELIX THERAPEUTICS, INC. 2025-07-24 US disclosed
US-12295959-B2 Phenoxy and benzyloxy substituted psychoplastogens and uses thereof DELIX THERAPEUTICS, INC. (US) 2025-05-13 US disclosed
EP-4448531-A1 PHENOXY AND BENZYLOXY SUBSTITUTED PSYCHOPLASTOGENS AND USES THEREOF Delix Therapeutics, Inc. (US) 2024-10-23 EP disclosed
US-20240335454-A1 PHENOXY AND BENZYLOXY SUBSTITUTED PSYCHOPLASTOGENS AND USES THEREOF DELIX THERAPEUTICS, INC. 2024-10-10 US disclosed
WO-2023114313-A1 PHENOXY AND BENZYLOXY SUBSTITUTED PSYCHOPLASTOGENS AND USES THEREOF DELIX THERAPEUTICS, INC. (US) 2023-06-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240335454-A1 PHENOXY AND BENZYLOXY SUBSTITUTED PSYCHOPLASTOGENS AND USES THEREOF GAP43, BDNF, GRIN2A S1PR2 1460/4885BAZ2B 618/4885TRPV1 2581/4885
US-12295959-B2 Phenoxy and benzyloxy substituted psychoplastogens and uses thereof GAP43, BDNF, GRIN2A S1PR2 1460/4885BAZ2B 618/4885TRPV1 2581/4885
US-20250235463-A1 PHENOXY AND BENZYLOXY SUBSTITUTED PSYCHOPLASTOGENS AND USES THEREOF GAP43, BDNF, GRIN2A S1PR2 1460/4885BAZ2B 618/4885TRPV1 2581/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.