Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.56 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.52 |
| ▸ | GRM5 | P41594 | 1/20 | 0.52 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.51 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2878827 | 0.85 | KDM4E (0.61) | GFERMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL421465 | 0.84 | SERPINE1 (0.65) | GFERMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL3050158 | 0.83 | POLB (0.56) | GFERMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL418492 | 0.82 | AKR1C4 (0.57) | GFERMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL418984 | 0.81 | GRIK1 (0.64) | MEN1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL420185 | 0.80 | SERPINE1 (0.77) | ALDH1A1KDM4EMAPTAKR1C4AKR1C3 | |
| SCHEMBL267931 | 0.79 | HPGD (0.57) | GFERMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL6720902 | 0.76 | MEN1 (1.00) | GFERMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL417914 | 0.76 | SERPINE1 (0.64) | MAPTAKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL418400 | 0.76 | SERPINE1 (0.60) | KMT2AALDH1A1KDM4EGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110294853-A1 | Bis Aromatic Compounds for Use in the Treatment of Inflammation | BIOLIPOX AB (SE) | 2011-12-01 | — | — | US | disclosed |
| WO-2010029300-A1 | BIS AROMATIC COMPOUNDS FOR USE IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2010-03-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110294853-A1 | Bis Aromatic Compounds for Use in the Treatment of Inflammation | LTC4S, LTB4R2, LTB4R | GFER 1283/4885MEN1 4133/4885KMT2A 3724/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.