Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRPR | P30550 | 17/20 | 0.76 |
| ▸ | PTH1R | Q03431 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bombesin SCHEMBL29711302 | 1.00 | GRPR (0.76) | GRPRPTH1R | |
| SCHEMBL29475770 | 0.94 | GRPR (0.72) | GRPR | |
| Bombesin SCHEMBL29364598 | 0.93 | GRPR (0.66) | GRPR | |
| SCHEMBL31738529 | 0.90 | GRPR (0.62) | GRPRPTH1R | |
| SCHEMBL29565297 | 0.90 | GRPR (0.68) | GRPR | |
| SCHEMBL31060626 | 0.88 | GRPR (0.58) | GRPRPTH1R | |
| SCHEMBL30783571 | 0.87 | GRPR (0.65) | GRPR | |
| Bombesin SCHEMBL29353003 | 0.86 | GRPR (0.70) | GRPR | |
| SCHEMBL30798936 | 0.85 | GRPR (0.81) | GRPR | |
| SCHEMBL16359497 | 0.84 | GRPR (0.74) | GRPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100323963-A1 | CONJUGATES OF DISORAZOLES AND THEIR DERIVATIVES WITH CELL-BINDING MOLECULES, NOVEL DISORAZOLE DERIVATIVES, PROCESSES OF MANUFACTURING AND USES THEREOF | AETERNA ZENTARIS GMBH (DE) | 2010-12-23 | — | — | US | claimed |
| US-20100317580-A1 | CONJUGATES OF DISORAZOLES AND THEIR DERIVATIVES WITH CELL-BINDING MOLECULES, NOVEL DISORAZOLE DERIVATIVES, PROCESSES OF MANUFACTURING AND USES THEREOF | AETERNA ZENTARIS GMBH (DE) | 2010-12-16 | — | — | US | claimed |
| CN-101578287-A | Conjugates of disorazoles and their derivatives with cell-binding molecules, novel disorazoles derivatives, process for their preparation and their use | AETERMA ZENTARIS GMBH (DE) | 2009-11-11 | — | — | CN | claimed |
| EP-2066679-A1 | CONJUGATES OF DISORAZOLES AND THEIR DERIVATIVES WITH CELL-BINDING MOLECULES, NOVEL DISORAZOLE DERIVATIVES, PROCESSES OF MANUFACTURING AND USES THEREOF | AEterna Zentaris GmbH (DE) | 2009-06-10 | — | — | EP | claimed |
| US-20080090758-A1 | CONJUGATES OF DISORAZOLES AND THEIR DERIVATIVES WITH CELL-BINDING MOLECULES, NOVEL DISORAZOLE DERIVATIVES, PROCESSES OF MANUFACTURING AND USES THEREOF | AETERNA ZENTARIS GMBH (DE) | 2008-04-17 | — | — | US | claimed |
| EP-1900742-A1 | Conjugates of disorazoles and their derivatives with cell-binding molecules, novel disorazole derivatives, processes of manufacturing and uses thereof | AEterna Zentaris GmbH (DE) | 2008-03-19 | — | — | EP | claimed |
| WO-2008028934-A1 | CONJUGATES OF DISORAZOLES AND THEIR DERIVATIVES WITH CELL-BINDING MOLECULES, NOVEL DISORAZOLE DERIVATIVES, PROCESSES OF MANUFACTURING AND USES THEREOF | AETERNA ZENTARIS GMBH (DE) | 2008-03-13 | — | — | WO | claimed |
| US-11033642-B2 | Multidentate bifunctional chelating agents for radionuclide complexation in diagnostics and therapy | UNIVERSITAT ZURICH (CH) | 2021-06-15 | — | — | US | disclosed |
| EP-3736269-A1 | A METHOD FOR FUNCTIONALIZATION OF AN AROMATIC AMINO ACID OR A NUCLEOBASE | CF Plus Chemicals s.r.o. (CZ) | 2020-11-11 | — | — | EP | disclosed |
| EP-3131585-B1 | MULTIDENTATE BIFUNCTIONAL CHELATING AGENTS FOR RADIONUCLIDE COMPLEXATION IN DIAGNOSTICS AND THERAPY | UNIV ZUERICH (CH) | 2020-07-15 | — | — | EP | disclosed |
| US-20170106106-A1 | MULTIDENTATE BIFUNCTIONAL CHELATING AGENTS FOR RADIONUCLIDE COMPLEXATION IN DIAGNOSTICS AND THERAPY | UNIVERSITAT ZURICH (CH) | 2017-04-20 | — | — | US | disclosed |
| EP-3131585-A1 | MULTIDENTATE BIFUNCTIONAL CHELATING AGENTS FOR RADIONUCLIDE COMPLEXATION IN DIAGNOSTICS AND THERAPY | Universität Zürich (CH) | 2017-02-22 | — | — | EP | disclosed |
| WO-2015140212-A1 | MULTIDENTATE BIFUNCTIONAL CHELATING AGENTS FOR RADIONUCLIDE COMPLEXATION IN DIAGNOSTICS AND THERAPY | Universität Zürich (CH) | 2015-09-24 | — | — | WO | disclosed |
| US-20100317580-A1 | CONJUGATES OF DISORAZOLES AND THEIR DERIVATIVES WITH CELL-BINDING MOLECULES, NOVEL DISORAZOLE DERIVATIVES, PROCESSES OF MANUFACTURING AND USES THEREOF | AETERNA ZENTARIS GMBH (DE) | 2010-12-16 | — | — | US | disclosed |
| US-7741277-B2 | Conjugates of disorazoles and their derivatives with cell-binding molecules, novel disorazole derivatives, processes of manufacturing and uses thereof | AETERNA ZENTARIS GMBH (DE) | 2010-06-22 | — | — | US | disclosed |
| CN-101578287-A | Conjugates of disorazoles and their derivatives with cell-binding molecules, novel disorazoles derivatives, process for their preparation and their use | AETERMA ZENTARIS GMBH (DE) | 2009-11-11 | — | — | CN | disclosed |
| EP-2066679-A1 | CONJUGATES OF DISORAZOLES AND THEIR DERIVATIVES WITH CELL-BINDING MOLECULES, NOVEL DISORAZOLE DERIVATIVES, PROCESSES OF MANUFACTURING AND USES THEREOF | AEterna Zentaris GmbH (DE) | 2009-06-10 | — | — | EP | disclosed |
| US-20080090758-A1 | CONJUGATES OF DISORAZOLES AND THEIR DERIVATIVES WITH CELL-BINDING MOLECULES, NOVEL DISORAZOLE DERIVATIVES, PROCESSES OF MANUFACTURING AND USES THEREOF | AETERNA ZENTARIS GMBH (DE) | 2008-04-17 | — | — | US | disclosed |
| EP-1900742-A1 | Conjugates of disorazoles and their derivatives with cell-binding molecules, novel disorazole derivatives, processes of manufacturing and uses thereof | AEterna Zentaris GmbH (DE) | 2008-03-19 | — | — | EP | disclosed |
| WO-2008028934-A1 | CONJUGATES OF DISORAZOLES AND THEIR DERIVATIVES WITH CELL-BINDING MOLECULES, NOVEL DISORAZOLE DERIVATIVES, PROCESSES OF MANUFACTURING AND USES THEREOF | AETERNA ZENTARIS GMBH (DE) | 2008-03-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170106106-A1 | MULTIDENTATE BIFUNCTIONAL CHELATING AGENTS FOR RADIONUCLIDE COMPLEXATION IN DIAGNOSTICS AND THERAPY | AOC1, XDH, FOLR1 | GRPR 461/4885PTH1R 1087/4885 |
| US-11033642-B2 | Multidentate bifunctional chelating agents for radionuclide complexation in diagnostics and therapy | AOC1, XDH, FOLR1 | GRPR 461/4885PTH1R 1087/4885 |
| US-20100323963-A1 | CONJUGATES OF DISORAZOLES AND THEIR DERIVATIVES WITH CELL-BINDING MOLECULES, NOVEL DISORAZOLE DERIVATIVES, PROCESSES OF MANUFACTURING AND USES THEREOF | EPCAM, CD99, PTMS | GRPR 860/4885PTH1R 685/4885 |
| US-20100317580-A1 | CONJUGATES OF DISORAZOLES AND THEIR DERIVATIVES WITH CELL-BINDING MOLECULES, NOVEL DISORAZOLE DERIVATIVES, PROCESSES OF MANUFACTURING AND USES THEREOF | EPCAM, CD99, PTMS | GRPR 860/4885PTH1R 685/4885 |
| US-20080090758-A1 | CONJUGATES OF DISORAZOLES AND THEIR DERIVATIVES WITH CELL-BINDING MOLECULES, NOVEL DISORAZOLE DERIVATIVES, PROCESSES OF MANUFACTURING AND USES THEREOF | EPCAM, CD99, PTMS | GRPR 860/4885PTH1R 685/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.