SCHEMBL3049400

SCHEMBL3049400

Oc1ccc(C2CC3CCC2C3)cc1

nearest known ligand 0.66

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.66
MEN1 O00255 1/20 0.66
POLB P06746 1/20 0.66
KMT2A Q03164 1/20 0.66
KDM1A O60341 2/20 0.46
SLC6A3 Q01959 8/20 0.44
ESR2 Q92731 6/20 0.40
ESR1 P03372 2/20 0.40
CYP2C9 P11712 2/20 0.40
SLC6A4 P31645 6/20 0.38
NPC1 O15118 1/20 0.38
ALDH1A1 P00352 1/20 0.38
MAPT P10636 1/20 0.38
PKM P14618 1/20 0.38
RAB9A P51151 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
CYP3A4 P08684 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21628750 0.90 MEN1 (0.53) GAAMEN1POLBKMT2AKDM1A
SCHEMBL900460 0.89 MEN1 (0.66) GAAMEN1POLBKMT2AKDM1A
SCHEMBL23338337 0.80 POLB (0.56) GAAMEN1POLBKMT2ASLC6A3
SCHEMBL21409728 0.80 MEN1 (0.56) GAAMEN1POLBKMT2ASLC6A3
SCHEMBL30501155 0.80 POLB (0.56) GAAMEN1POLBKMT2ASLC6A3
SCHEMBL23040796 0.80 MEN1 (0.61) GAAMEN1POLBKMT2ASLC6A3
SCHEMBL25171587 0.80 MEN1 (0.56) GAAMEN1POLBKMT2AKDM1A
SCHEMBL31109609 0.79 MEN1 (0.56) GAAMEN1POLBKMT2ASLC6A3
SCHEMBL17556991 0.79 MEN1 (0.56) GAAMEN1POLBKMT2AKDM1A
SCHEMBL17556992 0.79 MEN1 (0.56) GAAMEN1POLBKMT2AKDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 157 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1976995-B Polyarylate compositions GEN ELECTRIC 2010-06-09 CN claimed
CN-1976995-A Polyarylate compositions GEN ELECTRIC (US) 2007-06-06 CN claimed
US-20230406814-A2 NOVEL AROMATIC COMPOUNDS Xeniopro GmbH (DE) 2023-12-21 US disclosed
CN-117120548-A Polycarbonate resin composition and molded article 出光兴产株式会社 2023-11-24 CN disclosed
CN-107709460-B Polycarbonate resin composition and molded article thereof 出光兴产株式会社 2023-08-08 CN disclosed
CN-112689661-B Polycarbonate resin composition 出光兴产株式会社 2023-07-07 CN disclosed
CN-111527127-B Shaped body comprising a polycarbonate-polyorganosiloxane copolymer 出光兴产株式会社 2023-06-23 CN disclosed
CN-107735452-B Method for producing polycarbonate resin composition 出光兴产株式会社 2023-06-09 CN disclosed
US-20230150923-A1 NOVEL AROMATIC COMPOUNDS Xeniopro GmbH (DE) 2023-05-18 US disclosed
CN-116057106-A Polycarbonate resin composition and molded article thereof 出光兴产株式会社 2023-05-02 CN disclosed
CN-111527128-B Polycarbonate-polyorganosiloxane copolymer 出光兴产株式会社 2023-04-07 CN disclosed
CN-1383450-A Antibody molecule with specificity to human tumor necrosis factor alpha and application thereof CELLTECH R&D LTD (GB) 2002-12-04 CN disclosed
CN-1382188-A Blended polycarbonate compositions BAYER AG (DE) 2002-11-27 CN disclosed
CN-1379800-A Cyanate ester based thermoset compositions GEN ELECTRIC (US) 2002-11-13 CN disclosed
CN-1093147-C Low-birefringent organic optical component and spirobiindan polymer MITSUI CHEMICALS INC (JP) 2002-10-23 CN disclosed
CN-1333795-A dyed molded article MITSUI CHEMICALS INC (JP) 2002-01-30 CN disclosed
CN-1229817-A Cyanate ester based thermoset compositions GEN ELECTRIC (US) 1999-09-29 CN disclosed
CN-1218073-A Poly (phenylene ether) thermoset compositions GEN ELECTRIC (US) 1999-06-02 CN disclosed
CN-1175600-A Low-birefringent organic optical component and spirobiindan polymer MITSUI TOATSU CHEMICALS (JP) 1998-03-11 CN disclosed
US-4077962-A WATER INSOLUBLE, GREEN-YELLOW, SYNTHETIC FIBERS BAYER AKTIENGESELLSCHAFT (DT) 1978-03-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230150923-A1 NOVEL AROMATIC COMPOUNDS AHR, TYR, MUSK GAA 2354/4885MEN1 4341/4885POLB 3699/4885
US-20230406814-A2 NOVEL AROMATIC COMPOUNDS AHR, TYR, MUSK GAA 2354/4885MEN1 4341/4885POLB 3699/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.