Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 3/20 | 0.70 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.70 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.58 |
| ▸ | PGR | P06401 | 1/20 | 0.51 |
| ▸ | NOS1 | P29475 | 1/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.47 |
| ▸ | OGT | O15294 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 7/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 7/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | QPCT | Q16769 | 1/20 | 0.46 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.46 |
| ▸ | CDC7 | O00311 | 1/20 | 0.45 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1762375 | 1.00 | PDE3B (0.70) | PDE3BPDE3ACYP19A1PGRNOS1 | |
| SCHEMBL11251932 | 0.90 | PDE3B (0.68) | PDE3BPDE3ACYP19A1PGRNOS1 | |
| SCHEMBL1423560 | 0.83 | NPC1 (0.58) | PDE3BPDE3AALDH1A1 | |
| SCHEMBL26463815 | 0.83 | PDE3B (0.56) | PDE3BPDE3ACYP19A1PGRNOS1 | |
| SCHEMBL30494269 | 0.83 | PDE3B (0.56) | PDE3BPDE3ACYP19A1PGRNOS1 | |
| SCHEMBL17260655 | 0.82 | PDE3B (0.71) | PDE3BPDE3APGRNOS1OGT | |
| SCHEMBL1884142 | 0.81 | PDE3B (0.49) | PDE3BPDE3ACYP19A1PGRNOS1 | |
| SCHEMBL26463620 | 0.79 | PDE3B (0.62) | PDE3BPDE3ANOS1PIM1PIM2 | |
| SCHEMBL30494176 | 0.79 | PDE3B (0.62) | PDE3BPDE3ANOS1PIM1PIM2 | |
| SCHEMBL1878615 | 0.78 | KMO (0.55) | PDE3BPDE3ACYP19A1NOS1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250236613-A1 | SARM1 MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2025-07-24 | — | — | US | disclosed |
| EP-4423067-A1 | SARM1 MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2024-09-04 | — | — | EP | disclosed |
| CN-118176181-A | SARM1 modulators, their preparation and use | 维泰瑞隆有限公司 | 2024-06-11 | — | — | CN | disclosed |
| WO-2023072026-A1 | SARM1 MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-05-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250236613-A1 | SARM1 MODULATORS, PREPARATIONS, AND USES THEREOF | SARM1, ADRM1, SMN1; SMN2 | PDE3B 3476/4885PDE3A 3190/4885CYP19A1 4700/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.