SCHEMBL30494358

SCHEMBL30494358

O=c1[nH]cc([C@H]2C[C@H](O)[C@@H](COP(=O)(O)O)O2)c(=S)[nH]1

nearest known ligand 0.45

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TYMS P04818 7/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2888800 0.89 TYMS (0.48) TYMS
SCHEMBL25252324 0.80 FBP1 (0.48)
SCHEMBL346202 0.79 POLA1 (0.42) TYMS
SCHEMBL15810868 0.79 TYMS (0.39) TYMS
SCHEMBL31685443 0.77 TYMS (0.45) TYMS
SCHEMBL15810851 0.75 P2RY2 (0.42)
SCHEMBL10608402 0.73 TYMS (0.44) TYMS
SCHEMBL31685450 0.72 TYMS (0.54) TYMS
SCHEMBL4316736 0.71 TYMS (0.46) TYMS
SCHEMBL31398391 0.70 P2RY2 (0.49)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4463560-A1 C-NUCLEOSIDE MONOPHOSPHATE SYNTHESIS Uab Biomatter Designs (LT) 2024-11-20 EP disclosed
CN-118541490-A Synthesis of C-nucleoside monophosphates UAB生物物质设计公司 2024-08-23 CN disclosed
WO-2023131727-A1 C-NUCLEOSIDE MONOPHOSPHATE SYNTHESIS UAB BIOMATTER DESIGNS (LT) 2023-07-13 WO disclosed