Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.85 |
| ▸ | POLB | P06746 | 1/20 | 0.75 |
| ▸ | KRAS | P01116 | 10/20 | 0.74 |
| ▸ | TGM2 | P21980 | 1/20 | 0.71 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.70 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.70 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.70 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.64 |
| ▸ | IMPDH2 | P12268 | 4/20 | 0.63 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphomethylphosphonic Acid Guanylate Ester SCHEMBL29941327 | 1.00 | NT5E (0.85) | NT5EPOLBKRASTGM2ENPP1 | |
| Phosphomethylphosphonic Acid Guanosyl Ester SCHEMBL4312033 | 0.92 | NT5E (1.00) | NT5EKRASTGM2ENPP1 | |
| Phosphomethylphosphonic Acid Guanosyl Ester SCHEMBL21067782 | 0.92 | NT5E (1.00) | NT5EKRASTGM2ENPP1 | |
| Phosphomethylphosphonic Acid Guanosyl Ester SCHEMBL12714637 | 0.92 | NT5E (1.00) | NT5EKRASTGM2ENPP1 | |
| Phosphomethylphosphonic Acid Guanosyl Ester SCHEMBL12714656 | 0.92 | NT5E (1.00) | NT5EKRASTGM2ENPP1 | |
| E626 SCHEMBL25249751 | 0.90 | NT5E (0.77) | NT5EKRASTGM2P2RX3FUT5 | |
| SCHEMBL17072523 | 0.90 | TGM2 (0.82) | NT5EKRASTGM2ENPP1P2RX1 | |
| SCHEMBL80058 | 0.90 | TGM2 (0.82) | NT5EKRASTGM2ENPP1P2RX1 | |
| SCHEMBL13210265 | 0.90 | TGM2 (0.82) | NT5EKRASTGM2ENPP1P2RX1 | |
| SCHEMBL23969756 | 0.90 | TGM2 (0.82) | NT5EKRASTGM2ENPP1P2RX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023149801-A1 | METHOD FOR PREPARING A CONFORMATION-SPECIFIC ANTIBODY. | ERASMUS UNIVERSITY MEDICAL CENTER ROTTERDAM (NL) | 2023-08-10 | — | — | WO | claimed |
| US-12146168-B2 | Human CGAS-DNA complex and encoded protein | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2024-11-19 | — | — | US | disclosed |
| WO-2023149801-A1 | METHOD FOR PREPARING A CONFORMATION-SPECIFIC ANTIBODY. | ERASMUS UNIVERSITY MEDICAL CENTER ROTTERDAM (NL) | 2023-08-10 | — | — | WO | disclosed |