Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.57 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.53 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.53 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.53 |
| ▸ | SCN1A | P35498 | 1/20 | 0.53 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.53 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL566705 | 1.00 | DRD2 (0.57) | DRD2ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL568055 | 0.86 | DRD2 (0.55) | DRD2ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL566715 | 0.84 | DRD2 (0.63) | DRD2ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL567316 | 0.84 | DRD2 (0.63) | DRD2ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL567487 | 0.84 | DRD2 (0.57) | DRD2ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL567617 | 0.82 | ADRA2A (0.61) | DRD2ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL3039235 | 0.80 | DRD2 (0.54) | DRD2ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL567283 | 0.80 | ADRA2A (0.58) | DRD2ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL3044732 | 0.80 | DRD2 (0.64) | DRD2ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL3044736 | 0.80 | DRD2 (0.64) | DRD2ADRA2AADRA2BADRA2CADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4460298-A1 | Alpha2-ADRENOCEPTOR SUBTYPE C ANTAGONISTS FOR THE TREATMENT OF SLEEP APNEA | Bayer Aktiengesellschaft (DE) | 2024-11-13 | — | — | EP | claimed |
| WO-2023131640-A1 | α2-ADRENOCEPTOR SUBTYPE C ANTAGONISTS FOR THE TREATMENT OF SLEEP APNEA | BAYER AKTIENGESELLSCHAFT (DE) | 2023-07-13 | — | — | WO | claimed |
| EP-4460298-A1 | Alpha2-ADRENOCEPTOR SUBTYPE C ANTAGONISTS FOR THE TREATMENT OF SLEEP APNEA | Bayer Aktiengesellschaft (DE) | 2024-11-13 | — | — | EP | disclosed |
| WO-2023131640-A1 | α2-ADRENOCEPTOR SUBTYPE C ANTAGONISTS FOR THE TREATMENT OF SLEEP APNEA | BAYER AKTIENGESELLSCHAFT (DE) | 2023-07-13 | — | — | WO | disclosed |