Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 6/20 | 0.41 |
| ▸ | MME | P08473 | 2/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30728878 | 0.92 | MME (0.43) | MMELTA4H | |
| SCHEMBL1666827 | 0.92 | MME (0.44) | MMELTA4H | |
| SCHEMBL1666829 | 0.92 | MME (0.44) | MMELTA4H | |
| SCHEMBL29531330 | 0.92 | MME (0.44) | MMELTA4H | |
| SCHEMBL31073567 | 0.92 | BACE1 (0.42) | BACE1 | |
| SCHEMBL34470345 | 0.91 | MME (0.42) | MMELTA4HOPRM1OPRD1OPRK1 | |
| Water SCHEMBL29559377 | 0.91 | MME (0.44) | MMELTA4H | |
| SCHEMBL30656926 | 0.91 | MMP2 (0.40) | BACE1 | |
| SCHEMBL30656920 | 0.91 | NPY4R (0.38) | OPRD1 | |
| SCHEMBL29442611 | 0.90 | MME (0.41) | MMELTA4HOPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230190887-A1 | TARGETING G3BP AGGREGATION TO PREVENT NEURODEGENERATION | UNIVERSITY OF SOUTH CAROLINA (US) | 2023-06-22 | — | — | US | disclosed |