Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 14/20 | 0.40 |
| ▸ | MMP9 | P14780 | 10/20 | 0.40 |
| ▸ | MMP8 | P22894 | 10/20 | 0.40 |
| ▸ | MMP1 | P03956 | 8/20 | 0.38 |
| ▸ | BACE1 | P56817 | 3/20 | 0.37 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.36 |
| ▸ | MMP3 | P08254 | 3/20 | 0.36 |
| ▸ | MMP7 | P09237 | 3/20 | 0.36 |
| ▸ | FCER2 | P06734 | 1/20 | 0.36 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.35 |
| ▸ | ADAM12 | O43184 | 1/20 | 0.35 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
| ▸ | MMP15 | P51511 | 1/20 | 0.35 |
| ▸ | MMP16 | P51512 | 1/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.35 |
| ▸ | ADAM9 | Q13443 | 1/20 | 0.35 |
| ▸ | MMP26 | Q9NRE1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30656920 | 0.92 | NPY4R (0.38) | MMP1KISS1RFCER2 | |
| SCHEMBL30495730 | 0.91 | BACE1 (0.41) | BACE1 | |
| SCHEMBL2181812 | 0.88 | BACE1 (0.34) | MMP8MMP1BACE1KISS1R | |
| SCHEMBL30728878 | 0.85 | MME (0.43) | — | |
| SCHEMBL31073567 | 0.84 | BACE1 (0.42) | MMP2MMP9BACE1MMP7MMP12 | |
| SCHEMBL30656930 | 0.84 | BMP1 (0.39) | MMP2MMP9MMP8MMP1MMP3 | |
| SCHEMBL29886675 | 0.83 | BACE1 (0.40) | BACE1 | |
| SCHEMBL29442611 | 0.83 | MME (0.41) | — | |
| SCHEMBL30192164 | 0.83 | BACE1 (0.36) | BACE1 | |
| SCHEMBL1666827 | 0.82 | MME (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230357320-A1 | HELICAL STAPLED PEPTIDES AND USES THEREOF | PARABILIS MEDICINES, INC. | 2023-11-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230357320-A1 | HELICAL STAPLED PEPTIDES AND USES THEREOF | ESRRB, ESR1, ESRRA | MMP2 413/4885MMP9 547/4885MMP8 199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.