Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | MITF | O75030 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | FGF1 | P05230 | 1/20 | 0.33 |
| ▸ | FGF2 | P09038 | 1/20 | 0.33 |
| ▸ | VEGFA | P15692 | 1/20 | 0.33 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30496607 | 0.96 | LMNA (0.56) | LMNAHTTSMN1; SMN2NPC1MITF | |
| SCHEMBL30496583 | 0.96 | LMNA (0.49) | LMNAHTTSMN1; SMN2NPC1MITF | |
| SCHEMBL30496599 | 0.92 | LMNA (0.52) | LMNAHTTSMN1; SMN2NPC1MITF | |
| SCHEMBL30496584 | 0.77 | LMNA (0.74) | LMNAHTTSMN1; SMN2NPC1MITF | |
| SCHEMBL29709820 | 0.70 | LMNA (0.84) | LMNAHTTSMN1; SMN2NPC1MITF | |
| SCHEMBL29709864 | 0.70 | LMNA (1.00) | LMNAHTTSMN1; SMN2NPC1MITF | |
| SCHEMBL29709886 | 0.68 | LMNA (1.00) | LMNAHTTSMN1; SMN2NPC1MITF | |
| Nagilactone SCHEMBL30496600 | 0.64 | LMNA (0.63) | LMNAHTTSMN1; SMN2NPC1MITF | |
| Nagilactone C SCHEMBL29709870 | 0.64 | LMNA (0.63) | LMNAHTTSMN1; SMN2NPC1MITF | |
| Nagilactone SCHEMBL29709880 | 0.64 | LMNA (0.63) | LMNAHTTSMN1; SMN2NPC1MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107405330-B | Bamboo Bai ester compound with hypolipidemic activity, and preparation method and application thereof | 中国科学院上海药物研究所 | 2023-08-01 | — | — | CN | disclosed |