Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | RECQL | P46063 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.50 |
| ▸ | GLA | P06280 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.48 |
| ▸ | TSHR | P16473 | 5/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 5/20 | 0.47 |
| ▸ | CASP1 | P29466 | 5/20 | 0.47 |
| ▸ | CASP7 | P55210 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30899106 | 0.94 | PTGER4 (0.48) | KCNH2IRAK4ALDH1A1RECQLLMNA | |
| SCHEMBL29924458 | 0.94 | PTGER4 (0.48) | KCNH2IRAK4ALDH1A1RECQLLMNA | |
| SCHEMBL22029484 | 0.81 | BRD4 (0.51) | ALDH1A1RECQLKDM4EPTGER4HSD17B10 | |
| SCHEMBL30497309 | 0.81 | BRD4 (0.52) | ALDH1A1RECQLKDM4EPTGER4HSD17B10 | |
| SCHEMBL30497271 | 0.79 | BRD4 (0.47) | ALDH1A1RECQLKDM4EGLAMAPT | |
| SCHEMBL30899119 | 0.79 | KCNH2 (0.46) | KCNH2IRAK4ALDH1A1RECQLLMNA | |
| SCHEMBL24142895 | 0.74 | KCNH2 (0.69) | KCNH2IRAK4ALDH1A1RECQLLMNA | |
| SCHEMBL10285226 | 0.74 | ALDH1A1 (0.66) | KCNH2ALDH1A1LMNAKDM4EGLA | |
| SCHEMBL29056691 | 0.74 | PTGER4 (0.58) | KCNH2IRAK4ALDH1A1RECQLLMNA | |
| SCHEMBL13011128 | 0.73 | PTGER4 (0.60) | ALDH1A1KDM4EPTGER4HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12497382-B2 | GLP-1R modulating compounds | GILEAD SCIENCES, INC. (US) | 2025-12-16 | — | — | US | disclosed |
| US-20230391747-A1 | GLP-1R MODULATING COMPOUNDS | GILEAD SCIENCES, INC. | 2023-12-07 | — | — | US | disclosed |
| US-11702404-B2 | GLP-1R modulating compounds | GILEAD SCIENCES, INC. (US) | 2023-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11702404-B2 | GLP-1R modulating compounds | GLP1R, GIPR, GPR119 | KCNH2 3295/4885IRAK4 995/4885ALDH1A1 3556/4885 |
| US-20230391747-A1 | GLP-1R MODULATING COMPOUNDS | GLP1R, GIPR, GPR119 | KCNH2 3295/4885IRAK4 995/4885ALDH1A1 3556/4885 |
| US-12497382-B2 | GLP-1R modulating compounds | GLP1R, GIPR, GPR119 | KCNH2 3295/4885IRAK4 995/4885ALDH1A1 3556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.