Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 5/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 15/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | APOL1 | O14791 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29076335 | 1.00 | CTSB (0.41) | CTSBCTSSCTSKCFTRAPOL1 | |
| SCHEMBL29076337 | 1.00 | CTSB (0.41) | CTSBCTSSCTSKCFTRAPOL1 | |
| SCHEMBL30497450 | 1.00 | CTSB (0.41) | CTSBCTSSCTSKCFTRAPOL1 | |
| SCHEMBL30497443 | 0.89 | CTSK (0.44) | CTSBCTSSCTSK | |
| SCHEMBL30497448 | 0.89 | CTSK (0.44) | CTSBCTSSCTSK | |
| SCHEMBL29076234 | 0.89 | CTSK (0.44) | CTSBCTSSCTSK | |
| SCHEMBL29076231 | 0.89 | CTSK (0.44) | CTSBCTSSCTSK | |
| SCHEMBL25309469 | 0.84 | CTSB (0.47) | CTSBCTSSCTSK | |
| SCHEMBL30497446 | 0.84 | CTSB (0.47) | CTSBCTSSCTSK | |
| SCHEMBL30497449 | 0.82 | CTSK (0.51) | CTSBCTSSCTSKCFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118742549-A | Cathepsin K inhibitor, preparation method and application thereof | 山东新时代药业有限公司 | 2024-10-01 | — | — | CN | claimed |
| CN-116514804-A | Cathepsin K inhibitor, preparation method and application thereof | 山东新时代药业有限公司 | 2023-08-01 | — | — | CN | claimed |
| CN-118742549-A | Cathepsin K inhibitor, preparation method and application thereof | 山东新时代药业有限公司 | 2024-10-01 | — | — | CN | disclosed |