Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL1 | P09936 | 5/20 | 0.48 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | IL1B | P01584 | 2/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.38 |
| ▸ | KLK7 | P49862 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20294486 | 0.88 | CD274 (0.40) | CD274 | |
| SCHEMBL15416639 | 0.78 | IRAK1 (0.53) | USP30IRAK1IRAK4 | |
| SCHEMBL15416415 | 0.78 | IRAK1 (0.53) | USP30IRAK1IRAK4 | |
| SCHEMBL16713457 | 0.78 | IRAK1 (0.53) | USP30IRAK1IRAK4 | |
| SCHEMBL25285595 | 0.77 | FPR3 (0.43) | UCHL1USP30ALOX5APFEN1IL1B | |
| SCHEMBL15270775 | 0.77 | PDE8B (0.43) | UCHL1ALOX5APFEN1IL1BP2RX7 | |
| SCHEMBL1703169 | 0.77 | PDE8B (0.47) | ALOX5APFEN1IL1BP2RX7ALDH1A1 | |
| SCHEMBL28116128 | 0.77 | PDE8B (0.43) | UCHL1ALOX5APFEN1IL1BP2RX7 | |
| SCHEMBL1703170 | 0.77 | PDE8B (0.47) | ALOX5APFEN1IL1BP2RX7ALDH1A1 | |
| SCHEMBL22761790 | 0.76 | MEN1 (0.42) | UCHL1USP30ALOX5APFEN1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230226062-A1 | HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS | INCYTE CORPORATION | 2023-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230226062-A1 | HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS | CD274, PDCD1, PDCD1LG2 | UCHL1 3476/4885USP30 4206/4885ALOX5AP 1445/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.