Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 11/20 | 0.45 |
| ▸ | BTK | Q06187 | 1/20 | 0.41 |
| ▸ | HCK | P08631 | 2/20 | 0.41 |
| ▸ | SRC | P12931 | 2/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | LYN | P07948 | 1/20 | 0.41 |
| ▸ | FRK | P42685 | 1/20 | 0.41 |
| ▸ | BLK | P51451 | 1/20 | 0.41 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.39 |
| ▸ | ABL1 | P00519 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | KDR | P35968 | 2/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.39 |
| ▸ | PRKDC | P78527 | 2/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29052739 | 1.00 | MAP4K4 (0.49) | MAP4K4NAMPTBTKHCKSRC | |
| SCHEMBL29052499 | 0.82 | NAMPT (0.40) | MAP4K4NAMPTBTKLCKKIT | |
| SCHEMBL29052482 | 0.82 | MAP4K4 (0.49) | MAP4K4NAMPTHCKSRCLCK | |
| SCHEMBL30499549 | 0.82 | MAP4K4 (0.49) | MAP4K4NAMPTHCKSRCLCK | |
| SCHEMBL30499541 | 0.76 | MAP4K4 (0.62) | MAP4K4HCKSRCLCKFYN | |
| SCHEMBL29052462 | 0.76 | MAP4K4 (0.62) | MAP4K4HCKSRCLCKFYN | |
| SCHEMBL30367031 | 0.68 | NAMPT (0.43) | MAP4K4NAMPTLCKLYNFRK | |
| SCHEMBL22418461 | 0.68 | FLT3 (0.62) | MAP4K4HCKSRCLCKFYN | |
| SCHEMBL24891722 | 0.67 | NAMPT (0.63) | NAMPTKITCDK7CDK13CDK12 | |
| SCHEMBL15587426 | 0.67 | MAP4K4 (1.00) | MAP4K4HCKSRCPIK3CDABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116437918-A | Pyrazolopyridine compounds as TAM inhibitors | 上海德琪医药科技有限公司 | 2023-07-14 | — | — | CN | disclosed |