Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.49 |
| ▸ | SRC | P12931 | 3/20 | 0.44 |
| ▸ | HCK | P08631 | 2/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | LYN | P07948 | 1/20 | 0.44 |
| ▸ | FRK | P42685 | 1/20 | 0.44 |
| ▸ | BLK | P51451 | 1/20 | 0.44 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.44 |
| ▸ | TYRO3 | Q06418 | 8/20 | 0.42 |
| ▸ | MERTK | Q12866 | 8/20 | 0.41 |
| ▸ | AXL | P30530 | 2/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.41 |
| ▸ | ABL1 | P00519 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.41 |
| ▸ | PRKDC | P78527 | 2/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29052482 | 1.00 | MAP4K4 (0.49) | MAP4K4SRCHCKLCKFYN | |
| SCHEMBL29052739 | 0.82 | MAP4K4 (0.49) | MAP4K4SRCHCKLCKFYN | |
| SCHEMBL30499545 | 0.82 | MAP4K4 (0.49) | MAP4K4SRCHCKLCKFYN | |
| SCHEMBL29052476 | 0.82 | DGAT1 (0.42) | MAP4K4SRCHCKTYRO3MERTK | |
| Trifluoroacetic Acid SCHEMBL30367156 | 0.81 | DGAT1 (0.44) | MAP4K4TYRO3MERTKAXLPIK3CD | |
| Trifluoroacetic Acid SCHEMBL29052474 | 0.81 | DGAT1 (0.44) | MAP4K4TYRO3MERTKAXLPIK3CD | |
| SCHEMBL29052462 | 0.76 | MAP4K4 (0.62) | MAP4K4SRCHCKLCKFYN | |
| SCHEMBL30499541 | 0.76 | MAP4K4 (0.62) | MAP4K4SRCHCKLCKFYN | |
| SCHEMBL29052448 | 0.75 | TYRO3 (0.72) | TYRO3MERTKAXL | |
| SCHEMBL30367356 | 0.69 | DGAT1 (0.42) | SRCLCKFYNLYNBLK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116437918-A | Pyrazolopyridine compounds as TAM inhibitors | 上海德琪医药科技有限公司 | 2023-07-14 | — | — | CN | disclosed |