Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 6/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3657469 | 1.00 | APP (0.46) | APPMAOBIDO1TP53CYP3A4 | |
| SCHEMBL1607526 | 0.85 | MAOB (0.48) | APPMAOBTP53CYP3A4LMNA | |
| SCHEMBL6089644 | 0.84 | APP (0.41) | APPMAOBCYP1A2CYP2D6MAPK1 | |
| SCHEMBL29584039 | 0.82 | MAPK1 (0.46) | APPLMNACYP1A2CYP2D6MAPK1 | |
| SCHEMBL670276 | 0.82 | MAPK1 (0.46) | APPLMNACYP1A2CYP2D6MAPK1 | |
| SCHEMBL23907052 | 0.81 | TP53 (0.43) | APPIDO1TP53CYP3A4LMNA | |
| SCHEMBL13846053 | 0.81 | CYP1A2 (0.53) | APPCYP1A2CYP2D6MAPK1CYP2C19 | |
| SCHEMBL10048853 | 0.81 | CYP1A2 (0.53) | APPMAOBCYP3A4CYP1A2CYP2D6 | |
| SCHEMBL2186305 | 0.80 | MAOB (0.42) | APPMAOBTP53CYP3A4LMNA | |
| SCHEMBL13845920 | 0.79 | CYP1A2 (0.51) | CYP1A2CYP2D6MAPK1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111170991-B | Antiproliferative compounds and methods of synthesis thereof | 细胞基因公司 | 2023-10-31 | — | — | CN | disclosed |
| CN-116323608-A | AMPK activator | 卡尔优普公司 | 2023-06-23 | — | — | CN | disclosed |