Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | TSHR | P16473 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | EDNRB | P24530 | 1/20 | 0.46 |
| ▸ | EDNRA | P25101 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CMA1 | P23946 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20386120 | 1.00 | SMN1; SMN2 (0.55) | SMN1; SMN2TSHRLMNAMAPTHTT | |
| SCHEMBL20379154 | 0.92 | LMNA (0.53) | SMN1; SMN2TSHRLMNAMAPTHTT | |
| SCHEMBL20379069 | 0.92 | LMNA (0.53) | SMN1; SMN2TSHRLMNAMAPTHTT | |
| SCHEMBL30501034 | 0.91 | TSHR (0.55) | SMN1; SMN2TSHRLMNAMAPTHTT | |
| SCHEMBL20386134 | 0.91 | TSHR (0.55) | SMN1; SMN2TSHRLMNAMAPTHTT | |
| SCHEMBL21565630 | 0.80 | SMN1; SMN2 (0.50) | SMN1; SMN2TSHRLMNAMAPTHTT | |
| SCHEMBL2883552 | 0.79 | LMNA (0.53) | SMN1; SMN2TSHRLMNAMAPTHTT | |
| SCHEMBL28878859 | 0.77 | SMN1; SMN2 (0.57) | SMN1; SMN2TSHRLMNAMAPTHTT | |
| SCHEMBL20379417 | 0.74 | SMN1; SMN2 (0.54) | SMN1; SMN2TSHRLMNAMAPTHTT | |
| SCHEMBL21387721 | 0.72 | THRB (0.48) | SMN1; SMN2TSHRLMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116462666-A | Cytoprotective compounds and uses thereof | 瑞士苏黎世联邦理工学院 | 2023-07-21 | — | — | CN | claimed |
| CN-116462666-A | Cytoprotective compounds and uses thereof | 瑞士苏黎世联邦理工学院 | 2023-07-21 | — | — | CN | disclosed |