SCHEMBL30501136

SCHEMBL30501136

Cc1ccc(Cn2nc(NC(=O)c3ccno3)c3ccccc32)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FSCN1 Q16658 1/20 0.57
HCRTR2 O43614 1/20 0.48
KMT2A Q03164 6/20 0.46
PYGM P11217 1/20 0.44
MEN1 O00255 4/20 0.43
ALDH1A1 P00352 2/20 0.43
ESR1 P03372 2/20 0.43
HSD17B10 Q99714 2/20 0.43
NPSR1 Q6W5P4 2/20 0.43
KDM4E B2RXH2 1/20 0.43
HPGD P15428 1/20 0.43
TSHR P16473 1/20 0.43
GAA P10253 1/20 0.43
HDAC3 O15379 1/20 0.42
HDAC1 Q13547 1/20 0.42
HDAC2 Q92769 1/20 0.42
HDAC10 Q969S8 1/20 0.42
HDAC8 Q9BY41 1/20 0.42
HDAC6 Q9UBN7 1/20 0.42
NCOR2 Q9Y618 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17028030 1.00 FSCN1 (0.57) FSCN1HCRTR2KMT2APYGMMEN1
SCHEMBL30501135 0.90 FSCN1 (0.58) FSCN1KMT2APYGMHDAC3HDAC1
SCHEMBL17038764 0.90 FSCN1 (0.58) FSCN1KMT2APYGMMEN1HSD17B10
SCHEMBL30501122 0.90 FSCN1 (0.58) FSCN1KMT2APYGMMEN1HSD17B10
SCHEMBL17199346 0.90 FSCN1 (0.58) FSCN1HCRTR2KMT2APYGMMEN1
SCHEMBL17038745 0.90 FSCN1 (0.58) FSCN1KMT2APYGMHDAC3HDAC1
SCHEMBL17038867 0.88 FSCN1 (0.75) FSCN1HDAC3HDAC1HDAC2HDAC10
SCHEMBL30695053 0.88 FSCN1 (0.75) FSCN1HDAC3HDAC1HDAC2HDAC10
SCHEMBL17038924 0.87 FSCN1 (0.55) FSCN1KMT2APYGMNPSR1HDAC3
SCHEMBL30694999 0.87 FSCN1 (0.55) FSCN1KMT2APYGMNPSR1HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260124177-A1 CO-THERAPIES INCLUDING A METASTASIS INHIBITOR NOVITA PHARMACEUTICALS, INC. (US) 2026-05-07 US disclosed
US-12508245-B2 Co-therapies including a metastasis inhibitor NOVITA PHARMACEUTICALS, INC. (US) 2025-12-30 US disclosed
US-20250333411-A1 COMPOUNDS AND METHODS FOR INHIBITING FASCIN CORNELL UNIVERSITY (US) 2025-10-30 US disclosed
US-12168658-B2 Compounds and methods for inhibiting fascin NOVITA PHARMACEUTICALS, INC. (US) 2024-12-17 US disclosed
US-20240124449-A1 COMPOUNDS AND METHODS FOR INHIBITING FASCIN NOVITA PHARMACEUTICALS, INC. (US) 2024-04-18 US disclosed
US-11858929-B2 Compounds and methods for inhibiting fascin CORNELL UNIVERSITY (US) 2024-01-02 US disclosed
US-20230310378-A1 CO-THERAPIES INCLUDING A METASTASIS INHIBITOR NOVITA PHARMACEUTICALS, INC. (US) 2023-10-05 US disclosed
US-11701342-B2 Co-therapies including a metastasis inhibitor CORNELL UNIVERSITY (US) 2023-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240124449-A1 COMPOUNDS AND METHODS FOR INHIBITING FASCIN FSCN1, MTPN, MYOF FSCN1 1/4885HCRTR2 3383/4885KMT2A 4757/4885
US-12508245-B2 Co-therapies including a metastasis inhibitor PDCD1, CD274, PDCD4 FSCN1 936/4885HCRTR2 3760/4885KMT2A 2544/4885
US-20250333411-A1 COMPOUNDS AND METHODS FOR INHIBITING FASCIN FSCN1, MTPN, MYOF FSCN1 1/4885HCRTR2 3383/4885KMT2A 4757/4885
US-11858929-B2 Compounds and methods for inhibiting fascin FSCN1, MTPN, MYOF FSCN1 1/4885HCRTR2 3383/4885KMT2A 4757/4885
US-20230310378-A1 CO-THERAPIES INCLUDING A METASTASIS INHIBITOR MIF, CXCL10, CCL2 FSCN1 1017/4885HCRTR2 2923/4885KMT2A 1480/4885
US-12168658-B2 Compounds and methods for inhibiting fascin FSCN1, MTPN, MYOF FSCN1 1/4885HCRTR2 3383/4885KMT2A 4757/4885
US-11701342-B2 Co-therapies including a metastasis inhibitor MIF, CXCL10, CCL2 FSCN1 1017/4885HCRTR2 2923/4885KMT2A 1480/4885
US-20260124177-A1 CO-THERAPIES INCLUDING A METASTASIS INHIBITOR CCR10, CCR4, OGFR FSCN1 3152/4885HCRTR2 33/4885KMT2A 3991/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.