Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 3/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CLK2 | P49760 | 1/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30501216 | 0.91 | DYRK1A (0.38) | CSF1RCHEK1DYRK1ACLK2LRRK2 | |
| SCHEMBL30501446 | 0.89 | IRAK4 (0.46) | CSF1RCHEK1ALDH1A1LRRK2TGFBR1 | |
| SCHEMBL30501359 | 0.88 | IRAK4 (0.45) | CSF1RCHEK1ALDH1A1LRRK2TGFBR1 | |
| SCHEMBL30501200 | 0.83 | IRAK4 (0.46) | CSF1RALDH1A1LRRK2TGFBR1ACVR1 | |
| SCHEMBL30501262 | 0.82 | PRKCA (0.39) | CHEK1LRRK2TGFBR1ACVR1ROCK2 | |
| SCHEMBL30501443 | 0.81 | CDK2 (0.40) | CSF1RCHEK1LRRK2TGFBR1ACVR1 | |
| SCHEMBL30501447 | 0.81 | PIK3CD (0.41) | ALDH1A1LRRK2TGFBR1ACVR1MAPT | |
| SCHEMBL30501385 | 0.81 | CSF1R (0.40) | CSF1RCHEK1ALDH1A1RPS6KA3TGFBR1 | |
| SCHEMBL30501226 | 0.81 | CDK2 (0.42) | ALDH1A1LRRK2TGFBR1ACVR1MAPT | |
| SCHEMBL30052799 | 0.79 | CDK2 (0.39) | CHEK1DYRK1ACLK2RPS6KA3TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111032642-B | Kinase inhibitors and methods of making and using the same | 里格尔药品股份有限公司 | 2023-07-18 | — | — | CN | claimed |
| CN-111032642-B | Kinase inhibitors and methods of making and using the same | 里格尔药品股份有限公司 | 2023-07-18 | — | — | CN | disclosed |