Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 13/20 | 0.50 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.47 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.46 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20598489 | 1.00 | IRAK4 (0.50) | IRAK4PIM1PIM3IRAK1KIF18A | |
| SCHEMBL30501448 | 0.84 | NTRK1 (0.57) | IRAK4PIM1PIM3IRAK1TSHR | |
| SCHEMBL20598735 | 0.84 | NTRK1 (0.57) | IRAK4PIM1PIM3IRAK1TSHR | |
| SCHEMBL20598394 | 0.83 | PIM1 (0.53) | IRAK4PIM1PIM3IRAK1TSHR | |
| SCHEMBL20598482 | 0.82 | PIM1 (0.51) | IRAK4PIM1PIM3IRAK1TSHR | |
| SCHEMBL30501501 | 0.82 | PIM1 (0.51) | IRAK4PIM1PIM3IRAK1TSHR | |
| SCHEMBL20598608 | 0.82 | IRAK4 (0.71) | IRAK4PIM1PIM3IRAK1KIF18A | |
| SCHEMBL28383371 | 0.82 | PIM1 (0.55) | IRAK4PIM1PIM3TSHRALDH1A1 | |
| SCHEMBL20598769 | 0.80 | ALDH1A1 (0.61) | TSHRALDH1A1NPSR1CYP1A2POLB | |
| SCHEMBL20598682 | 0.80 | TSHR (0.49) | IRAK4PIM1PIM3TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111032642-B | Kinase inhibitors and methods of making and using the same | 里格尔药品股份有限公司 | 2023-07-18 | — | — | CN | disclosed |