Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.55 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.53 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.47 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28383374 | 0.86 | PIM1 (0.53) | PIM1PIM3ALDH1A1TSHRNPSR1 | |
| SCHEMBL20598482 | 0.84 | PIM1 (0.51) | PIM1PIM3ALDH1A1TSHRNPSR1 | |
| SCHEMBL30501501 | 0.84 | PIM1 (0.51) | PIM1PIM3ALDH1A1TSHRNPSR1 | |
| SCHEMBL20598735 | 0.84 | NTRK1 (0.57) | PIM1PIM3ALDH1A1TSHRNPSR1 | |
| SCHEMBL30501448 | 0.84 | NTRK1 (0.57) | PIM1PIM3ALDH1A1TSHRNPSR1 | |
| SCHEMBL20598489 | 0.82 | IRAK4 (0.50) | PIM1PIM3ALDH1A1TSHRNPSR1 | |
| SCHEMBL30501365 | 0.82 | IRAK4 (0.50) | PIM1PIM3ALDH1A1TSHRNPSR1 | |
| SCHEMBL28379236 | 0.80 | IRAK4 (0.69) | PIM1PIM3ALDH1A1TSHRNPSR1 | |
| SCHEMBL28379784 | 0.80 | MAPK10 (0.74) | ALDH1A1TSHRNPSR1MAPK10KMT2A | |
| SCHEMBL20598031 | 0.79 | TSHR (0.58) | PIM1PIM3ALDH1A1TSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111032642-A | Kinase inhibitors and methods of making and using | 里格尔药品股份有限公司 | 2020-04-17 | — | — | CN | disclosed |