Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | PIM1 | P11309 | 1/20 | 0.48 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20598031 | 1.00 | TSHR (0.58) | TSHRKMT2AALDH1A1HPGDGAA | |
| SCHEMBL30501390 | 0.93 | TSHR (0.49) | TSHRKMT2AALDH1A1HPGDGAA | |
| SCHEMBL20598682 | 0.93 | TSHR (0.49) | TSHRKMT2AALDH1A1HPGDGAA | |
| SCHEMBL20598482 | 0.85 | PIM1 (0.51) | TSHRALDH1A1PIM1PIM3MAPT | |
| SCHEMBL30501501 | 0.85 | PIM1 (0.51) | TSHRALDH1A1PIM1PIM3MAPT | |
| SCHEMBL20598634 | 0.85 | TSHR (0.58) | TSHRKMT2AALDH1A1HPGDGAA | |
| SCHEMBL30501423 | 0.84 | PIM1 (0.46) | TSHRKMT2AALDH1A1PIM1PIM3 | |
| SCHEMBL20598222 | 0.84 | PIM1 (0.46) | TSHRKMT2AALDH1A1PIM1PIM3 | |
| SCHEMBL20598685 | 0.82 | CSF1R (0.49) | KMT2AALDH1A1PIM1PIM3MAPT | |
| SCHEMBL30501470 | 0.82 | CSF1R (0.49) | KMT2AALDH1A1PIM1PIM3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111032642-B | Kinase inhibitors and methods of making and using the same | 里格尔药品股份有限公司 | 2023-07-18 | — | — | CN | disclosed |