Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.48 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.45 |
| ▸ | ATR | Q13535 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20598682 | 1.00 | TSHR (0.49) | TSHRPIM1PIM3ALDH1A1KMT2A | |
| SCHEMBL30501386 | 0.93 | TSHR (0.58) | TSHRPIM1PIM3ALDH1A1KMT2A | |
| SCHEMBL20598031 | 0.93 | TSHR (0.58) | TSHRPIM1PIM3ALDH1A1KMT2A | |
| SCHEMBL20598735 | 0.85 | NTRK1 (0.57) | TSHRPIM1PIM3ALDH1A1KMT2A | |
| SCHEMBL30501448 | 0.85 | NTRK1 (0.57) | TSHRPIM1PIM3ALDH1A1KMT2A | |
| SCHEMBL20598372 | 0.85 | TSHR (0.49) | TSHRPIM1PIM3ALDH1A1KMT2A | |
| SCHEMBL30501479 | 0.84 | PIM1 (0.46) | TSHRPIM1PIM3ALDH1A1KMT2A | |
| SCHEMBL20598360 | 0.84 | PIM1 (0.46) | TSHRPIM1PIM3ALDH1A1KMT2A | |
| SCHEMBL20598757 | 0.82 | PIM1 (0.48) | TSHRPIM1PIM3ALDH1A1KMT2A | |
| SCHEMBL30501336 | 0.82 | PIM1 (0.48) | TSHRPIM1PIM3ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111032642-B | Kinase inhibitors and methods of making and using the same | 里格尔药品股份有限公司 | 2023-07-18 | — | — | CN | disclosed |