Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | HTR7 | P34969 | 2/20 | 0.49 |
| ▸ | HTR6 | P50406 | 2/20 | 0.49 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.44 |
| ▸ | Q9HBH1 | 2/20 | 0.43 | |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 3/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.39 |
| ▸ | PRNP | P04156 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28344805 | 1.00 | DRD2 (0.49) | DRD2HTR2AHTR7HTR6PRMT1 | |
| SCHEMBL20288065 | 1.00 | DRD2 (0.49) | DRD2HTR2AHTR7HTR6PRMT1 | |
| SCHEMBL801271 | 1.00 | DRD2 (0.49) | DRD2HTR2AHTR7HTR6PRMT1 | |
| SCHEMBL8739350 | 1.00 | DRD2 (0.49) | DRD2HTR2AHTR7HTR6PRMT1 | |
| SCHEMBL31069659 | 1.00 | DRD2 (0.49) | DRD2HTR2AHTR7HTR6PRMT1 | |
| SCHEMBL31069660 | 1.00 | DRD2 (0.49) | DRD2HTR2AHTR7HTR6PRMT1 | |
| SCHEMBL28889573 | 0.93 | PDF (0.53) | DRD2HTR2AHTR7HTR6PDF | |
| SCHEMBL28393566 | 0.93 | PDF (0.53) | DRD2HTR2AHTR7HTR6PDF | |
| SCHEMBL28592747 | 0.93 | PDF (0.53) | DRD2HTR2AHTR7HTR6PDF | |
| SCHEMBL28593684 | 0.93 | PDF (0.53) | DRD2HTR2AHTR7HTR6PDF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117659004-A | Phenothiazine polymerization inhibitor containing pyridoquinazolinone, and preparation method and application thereof | 万华化学集团股份有限公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-110312708-B | Luminescent materials for biological applications | 香港科技大学 | 2023-07-18 | — | — | CN | disclosed |