Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | IKBKE | Q14164 | 2/20 | 0.47 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.47 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | PRKACA | P17612 | 1/20 | 0.47 |
| ▸ | GRK5 | P34947 | 1/20 | 0.47 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.47 |
| ▸ | CDK8 | P49336 | 1/20 | 0.47 |
| ▸ | GSK3A | P49840 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23091246 | 1.00 | KDM4E (0.51) | KDM4EALDH1A1GAASMN1; SMN2POLB | |
| SCHEMBL23091159 | 0.82 | KDM4E (0.63) | KDM4EALDH1A1GAASMN1; SMN2POLB | |
| SCHEMBL30501653 | 0.82 | KDM4E (0.63) | KDM4EALDH1A1GAASMN1; SMN2POLB | |
| SCHEMBL30501703 | 0.81 | KDM4E (0.52) | KDM4EALDH1A1GAASMN1; SMN2POLB | |
| SCHEMBL18573543 | 0.81 | KDM4E (0.52) | KDM4EALDH1A1GAASMN1; SMN2POLB | |
| SCHEMBL23091163 | 0.80 | KDM4E (0.49) | KDM4EALDH1A1GAASMN1; SMN2NPC1 | |
| SCHEMBL18573541 | 0.79 | HSD17B1 (0.59) | KDM4EALDH1A1GAASMN1; SMN2POLB | |
| SCHEMBL23091253 | 0.78 | CDK8 (0.56) | KDM4EALDH1A1GAASMN1; SMN2NPC1 | |
| SCHEMBL23222451 | 0.77 | KDM4E (0.49) | KDM4EALDH1A1GAASMN1; SMN2POLB | |
| SCHEMBL23091259 | 0.77 | KDM4E (0.48) | KDM4EALDH1A1GAASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112004807-B | Compounds and pharmaceutical compositions comprising the same | 自体吞噬科学有限公司 | 2023-07-18 | — | — | CN | claimed |
| CN-112004807-B | Compounds and pharmaceutical compositions comprising the same | 自体吞噬科学有限公司 | 2023-07-18 | — | — | CN | disclosed |