Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 4/20 | 0.59 |
| ▸ | HSD17B2 | P37059 | 4/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | PRKACA | P17612 | 1/20 | 0.47 |
| ▸ | GRK5 | P34947 | 1/20 | 0.47 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.47 |
| ▸ | CDK8 | P49336 | 1/20 | 0.47 |
| ▸ | GSK3A | P49840 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23091259 | 0.90 | KDM4E (0.48) | HSD17B1HSD17B2KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL30501703 | 0.90 | KDM4E (0.52) | HSD17B1HSD17B2KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL18573543 | 0.90 | KDM4E (0.52) | HSD17B1HSD17B2KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL23091249 | 0.87 | SNCA (0.53) | HSD17B1HSD17B2KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL21625727 | 0.86 | HSD17B1 (0.52) | HSD17B1HSD17B2HDAC6KDM4EMAPT | |
| SCHEMBL30977648 | 0.86 | HSD17B1 (0.52) | HSD17B1HSD17B2HDAC6KDM4EMAPT | |
| SCHEMBL18573580 | 0.85 | HSD17B1 (0.55) | HSD17B1HSD17B2HDAC6KDM4EMAPT | |
| SCHEMBL30977649 | 0.84 | HSD17B1 (0.64) | HSD17B1HSD17B2HDAC6KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL30977640 | 0.83 | HSD17B1 (0.62) | HSD17B1HSD17B2HDAC6KDM4EMAPT | |
| SCHEMBL18573516 | 0.81 | ESRRG (0.63) | HSD17B1HSD17B2KDM4EMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3805210-B1 | NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | AUTOPHAGYSCIENCES INC (KR) | 2023-11-29 | — | — | EP | claimed |
| CN-112004807-B | Compounds and pharmaceutical compositions comprising the same | 自体吞噬科学有限公司 | 2023-07-18 | — | — | CN | claimed |
| US-11407744-B2 | Compound and pharmaceutical composition comprising same | Autophagysciences Inc. (KR) | 2022-08-09 | — | — | US | claimed |
| EP-3805210-A1 | NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | Autophagysciences, Inc (KR) | 2021-04-14 | — | — | EP | claimed |
| US-20210078987-A1 | NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | Autophagysciences Inc. (KR) | 2021-03-18 | — | — | US | claimed |
| EP-3814340-B1 | NOVEL CATECHOL DERIVATIVES OR SALT THEREOF, PROCESSES FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | HEXAPHARMATEC CO LTD (KR) | 2024-12-18 | — | — | EP | disclosed |
| US-12110281-B2 | Catechol derivatives or salt thereof, processes for preparing the same, and pharmaceutical compositions comprising the same | HEXAPHARMATEC CO., LTD. (KR) | 2024-10-08 | — | — | US | disclosed |
| CN-112437773-B | Catechol derivatives or salts thereof, process for preparing the same and pharmaceutical compositions containing the same | 六合医药科技有限公司 | 2024-06-11 | — | — | CN | disclosed |
| EP-3805210-B1 | NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | AUTOPHAGYSCIENCES INC (KR) | 2023-11-29 | — | — | EP | disclosed |
| EP-3805210-B1 | NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | AUTOPHAGYSCIENCES INC (KR) | 2023-11-29 | — | — | EP | disclosed |
| CN-112004807-B | Compounds and pharmaceutical compositions comprising the same | 自体吞噬科学有限公司 | 2023-07-18 | — | — | CN | disclosed |
| US-11407744-B2 | Compound and pharmaceutical composition comprising same | Autophagysciences Inc. (KR) | 2022-08-09 | — | — | US | disclosed |
| US-20210078987-A1 | NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | Autophagysciences Inc. (KR) | 2021-03-18 | — | — | US | disclosed |
| US-20210078987-A1 | NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | Autophagysciences Inc. (KR) | 2021-03-18 | — | — | US | disclosed |
| EP-3339299-B1 | NOVEL CATECHOL DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | AUTOPHAGYSCIENCES INC (KR) | 2021-03-03 | — | — | EP | disclosed |
| CN-112437773-A | Novel catechol derivative or salt thereof, method for producing the same, and pharmaceutical composition containing the same | 六合医药科技有限公司 | 2021-03-02 | — | — | CN | disclosed |
| CN-112004807-A | Novel compounds and pharmaceutical compositions comprising said compounds | 自体吞噬科学有限公司 | 2020-11-27 | — | — | CN | disclosed |
| WO-2020017878-A1 | NOVEL CATECHOL DERIVATIVES OR SALT THEREOF, PROCESSES FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | HEXAPHARMATEC CO., LTD. (KR) | 2020-01-23 | — | — | WO | disclosed |
| EP-3339299-A2 | NOVEL CATECHOL DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | Autophagysciences, Inc (KR) | 2018-06-27 | — | — | EP | disclosed |
| WO-2017034242-A2 | NOVEL CATECHOL DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 유영제약 | 2017-03-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12110281-B2 | Catechol derivatives or salt thereof, processes for preparing the same, and pharmaceutical compositions comprising the same | COMT, TYR, REN | HSD17B1 1028/4885HSD17B2 744/4885HDAC6 871/4885 |
| US-11407744-B2 | Compound and pharmaceutical composition comprising same | TFEB, ATG7, BECN1 | HSD17B1 3622/4885HSD17B2 3443/4885HDAC6 32/4885 |
| US-20210078987-A1 | NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | TFEB, ATG7, BECN1 | HSD17B1 3558/4885HSD17B2 3424/4885HDAC6 33/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.