SCHEMBL30503249

SCHEMBL30503249

CCN1CCN(CCCCc2ccc(OCOC)c(C(=O)OC)n2)CC1

nearest known ligand 0.40

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.40
ALDH1A1 P00352 5/20 0.39
THRB P10828 1/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
ACHE P22303 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
DRD2 P14416 2/20 0.34
DRD3 P35462 2/20 0.34
HTR1A P08908 1/20 0.34
HTR2A P28223 1/20 0.34
HTR2C P28335 1/20 0.34
HTR7 P34969 1/20 0.34
USP2 O75604 1/20 0.34
MAPK1 P28482 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29036794 1.00 KDM4E (0.40) KDM4EALDH1A1THRBMEN1KMT2A
SCHEMBL30503335 0.86 CCR3 (0.45) KDM4EALDH1A1TDP1HTR1AHTR7
SCHEMBL29036785 0.86 CCR3 (0.45) KDM4EALDH1A1TDP1HTR1AHTR7
SCHEMBL29036774 0.85 HTR1A (0.55) ALDH1A1SMN1; SMN2DRD2DRD3HTR1A
SCHEMBL30503302 0.85 HTR1A (0.55) ALDH1A1SMN1; SMN2DRD2DRD3HTR1A
SCHEMBL24228070 0.84 ALDH1A1 (0.39) KDM4EALDH1A1THRBMEN1KMT2A
SCHEMBL26192254 0.84 POLB (0.40) KDM4EALDH1A1MEN1KMT2AACHE
SCHEMBL24228082 0.83 ALDH1A1 (0.38) KDM4EALDH1A1THRBMEN1KMT2A
SCHEMBL30503241 0.81 CYP4A11 (0.43) KDM4E
SCHEMBL29036786 0.81 CYP4A11 (0.43) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116472267-A Butyrylcholinesterase reactivating agent 法兰西国由中央军队卫生服务局代表 2023-07-21 CN disclosed