Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | MGLL | Q99685 | 6/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29426678 | 1.00 | HTR2C (0.46) | HTR2CDRD2MGLLADRA1AKCNH2 | |
| SCHEMBL30503220 | 1.00 | HTR2C (0.46) | HTR2CDRD2MGLLADRA1AKCNH2 | |
| SCHEMBL29426841 | 0.85 | MGLL (0.50) | HTR2CDRD2MGLLADRA1AKCNH2 | |
| SCHEMBL30503263 | 0.85 | MGLL (0.50) | HTR2CDRD2MGLLADRA1AKCNH2 | |
| SCHEMBL29426750 | 0.85 | MGLL (0.50) | HTR2CDRD2MGLLADRA1AKCNH2 | |
| SCHEMBL30503287 | 0.82 | MGLL (0.44) | MGLLADRA1AKCNH2NPY5R | |
| SCHEMBL29427017 | 0.82 | MGLL (0.44) | MGLLADRA1AKCNH2NPY5R | |
| SCHEMBL29426725 | 0.82 | MGLL (0.44) | MGLLADRA1AKCNH2NPY5R | |
| SCHEMBL30503233 | 0.82 | MGLL (0.44) | MGLLADRA1AKCNH2NPY5R | |
| SCHEMBL18899130 | 0.80 | HTR2C (0.54) | HTR2CDRD2MGLLHTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116323557-A | Cyclobutylamide monoacylglycerol lipase modulators | 詹森药业有限公司 | 2023-06-23 | — | — | CN | claimed |