Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 9/20 | 0.50 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | DRD5 | P21918 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29426750 | 1.00 | MGLL (0.50) | MGLLHTR2CADRA2ADRD1DRD5 | |
| SCHEMBL29426841 | 1.00 | MGLL (0.50) | MGLLHTR2CADRA2ADRD1DRD5 | |
| SCHEMBL31308061 | 0.89 | HTR2C (0.41) | MGLLHTR2CADRA2ADRD1DRD5 | |
| SCHEMBL29426678 | 0.85 | HTR2C (0.46) | MGLLHTR2CADRA1AKCNH2NPY5R | |
| SCHEMBL30503259 | 0.85 | HTR2C (0.46) | MGLLHTR2CADRA1AKCNH2NPY5R | |
| SCHEMBL30503220 | 0.85 | HTR2C (0.46) | MGLLHTR2CADRA1AKCNH2NPY5R | |
| SCHEMBL29426891 | 0.83 | MEN1 (0.38) | MGLLADRA1AKCNH2NPY5R | |
| SCHEMBL29426767 | 0.83 | MEN1 (0.38) | MGLLADRA1AKCNH2NPY5R | |
| SCHEMBL30503329 | 0.83 | MEN1 (0.38) | MGLLADRA1AKCNH2NPY5R | |
| SCHEMBL23859669 | 0.80 | MGLL (0.60) | MGLLHTR2CP2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116323557-A | Cyclobutylamide monoacylglycerol lipase modulators | 詹森药业有限公司 | 2023-06-23 | — | — | CN | claimed |
| CN-116323557-A | Cyclobutylamide monoacylglycerol lipase modulators | 詹森药业有限公司 | 2023-06-23 | — | — | CN | disclosed |