⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15806544 | 0.81 | DEPTOR (0.47) | — | |
| Hydrochloric Acid SCHEMBL28009377 | 0.79 | DEPTOR (0.46) | — | |
| SCHEMBL392473 | 0.79 | RAPGEF4 (0.61) | — | |
| SCHEMBL30675253 | 0.79 | RAPGEF4 (0.61) | — | |
| SCHEMBL27972189 | 0.77 | — | — | |
| SCHEMBL1143757 | 0.75 | — | — | |
| SCHEMBL1488202 | 0.75 | — | — | |
| SCHEMBL357210 | 0.75 | — | — | |
| SCHEMBL16416590 | 0.75 | — | — | |
| SCHEMBL8269809 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109454956-A | A kind of adhesive waterproof coil and preparation method thereof | 山东坤岳防水材料股份有限公司 | 2019-03-12 | — | — | CN | claimed |
| CN-108057418-A | There is the modified zeolite adsorbent of absorption property to the orthophosphates in water body | 北京益清源环保科技有限公司 | 2018-05-22 | — | — | CN | claimed |
| CN-105980384-B | Macrocyclic compounds having a heterocyclic P2' group as factor XIA inhibitors | 百时美施贵宝公司 | 2019-11-15 | — | — | CN | disclosed |
| CN-105592850-B | The inhibitor of ACK1/TNK2 tyrosine kinase | H·李·莫菲特癌症中心研究所公司 | 2019-11-15 | — | — | CN | disclosed |
| CN-110433162-A | It can be used as the dihydronaphthridine and related compound of the kinase inhibitor for treating proliferative disease | DECIPHERA PHARMACEUTICALS LLC | 2019-11-12 | — | — | CN | disclosed |
| CN-110403938-A | It can be used as the dihydronaphthridine and related compound of the kinase inhibitor for treating proliferative disease | DECIPHERA PHARMACEUTICALS LLC | 2019-11-05 | — | — | CN | disclosed |
| CN-110300579-A | Sulfamoyl aryl derivatives and its purposes for being used to treat liver fibrosis as drug | 詹森药业有限公司 | 2019-10-01 | — | — | CN | disclosed |
| CN-110248937-A | 4, 5-Cyclic 1,2, 4-triazolones | 拜耳股份有限公司 | 2019-09-17 | — | — | CN | disclosed |
| CN-110218182-A | IDO inhibitor | 南京亘泰医药技术有限公司 | 2019-09-10 | — | — | CN | disclosed |
| CN-110156786-A | Pyrimido-cyclic compounds, process for their preparation and their use | 上海青煜医药科技有限公司 | 2019-08-23 | — | — | CN | disclosed |
| CN-110003076-A | Sulfamoyl pyrrole amides derivative and its purposes for being used to treat hepatitis B as drug | 爱尔兰詹森科学公司 | 2019-07-12 | — | — | CN | disclosed |
| CN-1097418-A | The preparation method and its usage of 8-chloroquinolone carboxylic acid derivative | LI YONGKANG (CN) | 1995-01-18 | — | — | CN | disclosed |
| CN-1012613-B | PROCESS FOR PREPN. OF QUINONECARBOXYLIC ACID DERIVATIVE | KYORIN SEIYAKU KK (JP) | 1991-05-15 | — | — | CN | disclosed |
| CN-1011587-B | PROCESS FOR THE PREPARATION OF QUINOLONECARBOXYLIC ACID DERIVATIVES AND THEIR USE | KYORIN SEIYAKU KK (JP) | 1991-02-13 | — | — | CN | disclosed |
| CN-1010778-B | Process for preparing quinoline carboxylic acid derivatives | KYORIN SEIYAKU KK (JP) | 1990-12-12 | — | — | CN | disclosed |
| CN-1007150-B | SYNTHESIS OF 2,4-DICHLOR-5-FLUOR BENZOIC ACID | TIANJIN PHARMACEUTIC INDUSTRY (CN) | 1990-03-14 | — | — | CN | disclosed |
| CN-1031074-A | 2,4-two chloro-5-fluorobenzoic acids synthetic | TIANJIN RESEARCH INST OF MEDIC (CN) | 1989-02-15 | — | — | CN | disclosed |
| CN-86102363-A | The preparation method of Carbostyril carboxylic acid derivatives and application thereof | — | 1987-01-21 | — | — | CN | disclosed |
| CN-85104693-A | The preparation method of quinoline carboxylic acid derivative | KYORIN SEIYAKU KK (JP) | 1986-09-03 | — | — | CN | disclosed |
| CN-85109026-A | The preparation method and its usage of Carbostyril carboxylic acid derivatives | — | 1986-07-30 | — | — | CN | disclosed |