SCHEMBL30503510

SCHEMBL30503510

CCCCOc1nc(N)c2[nH]c(=O)n(Cc3ccc(CN)cc3)c2n1

nearest known ligand 0.84

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 19/20 0.84
IL6 P05231 11/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22347124 1.00 TLR7 (0.84) TLR7IL6
SCHEMBL1145915 0.92 TLR7 (0.84) TLR7IL6
SCHEMBL20740720 0.91 TLR7 (1.00) TLR7IL6
SCHEMBL26354073 0.91 TLR7 (0.82) TLR7IL6
Hydrochloric Acid SCHEMBL1146402 0.91 TLR7 (0.82) TLR7IL6
SCHEMBL24247632 0.89 TLR7 (0.82) TLR7IL6
SCHEMBL1146578 0.89 TLR7 (0.79) TLR7IL6
SCHEMBL1146437 0.88 TLR7 (0.78) TLR7IL6
SCHEMBL29475674 0.87 TLR7 (0.79) TLR7IL6
SCHEMBL1146575 0.87 TLR7 (0.79) TLR7IL6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119455003-A Compositions, methods and uses comprising antibody-TLR agonist conjugates AMBRX公司 2025-02-18 CN disclosed
CN-119455004-A Compositions, methods and uses comprising antibody-TLR agonist conjugates AMBRX公司 2025-02-18 CN disclosed
CN-113660957-B Compositions, methods and uses comprising antibody-TLR agonist conjugates AMBRX公司 2024-12-13 CN disclosed
CN-116457023-A antibody-TLR agonist conjugates, methods and uses thereof AMBRX公司 2023-07-18 CN disclosed