Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12889638 | 1.00 | MAT2A (0.34) | MAT2AKDM4EPTGDR2POLBIDO1 | |
| SCHEMBL12889714 | 0.81 | NOS3 (0.42) | KDM4EALDH1A1 | |
| SCHEMBL15031283 | 0.80 | KMT2A (0.37) | MAT2AKDM4EALDH1A1 | |
| SCHEMBL30503542 | 0.79 | MAT2A (0.33) | MAT2AIDO1LRRK2 | |
| SCHEMBL21589013 | 0.79 | HASPIN (0.37) | MAT2AIDO1LRRK2BRD4 | |
| SCHEMBL26631307 | 0.79 | MAT2A (0.33) | MAT2AIDO1LRRK2 | |
| SCHEMBL22824052 | 0.78 | MAT2A (0.36) | MAT2APTGDR2 | |
| SCHEMBL29365650 | 0.78 | MAT2A (0.36) | MAT2APTGDR2 | |
| SCHEMBL15333670 | 0.77 | — | — | |
| SCHEMBL20132721 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116323557-A | Cyclobutylamide monoacylglycerol lipase modulators | 詹森药业有限公司 | 2023-06-23 | — | — | CN | disclosed |