Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.59 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.41 |
| ▸ | MERTK | Q12866 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TDP2 | O95551 | 1/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | CCR4 | P51679 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19407671 | 1.00 | CRHBP (0.59) | CRHBPCRHR2MEN1KMT2AL3MBTL1 | |
| SCHEMBL6690974 | 0.82 | CRHBP (0.41) | CRHBPCRHR2MEN1KMT2AL3MBTL1 | |
| SCHEMBL30531704 | 0.82 | CRHBP (0.41) | CRHBPCRHR2MEN1KMT2AL3MBTL1 | |
| SCHEMBL29586509 | 0.79 | POLB (0.50) | CRHBPCRHR2KMT2AMAPTGRM4 | |
| SCHEMBL13865706 | 0.79 | GRM4 (0.41) | CRHBPCRHR2MEN1KMT2AMAPT | |
| SCHEMBL15195554 | 0.79 | CRHBP (0.42) | CRHBPCRHR2MEN1KMT2AL3MBTL1 | |
| SCHEMBL15300740 | 0.77 | CRHBP (0.41) | CRHBPCRHR2MEN1KMT2AL3MBTL1 | |
| SCHEMBL16405117 | 0.77 | CRHBP (0.41) | CRHBPCRHR2MEN1KMT2AL3MBTL1 | |
| SCHEMBL29144010 | 0.77 | CRHBP (0.41) | CRHBPCRHR2MEN1KMT2AL3MBTL1 | |
| SCHEMBL17477974 | 0.77 | CRHBP (0.41) | CRHBPCRHR2MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4735430-A1 | MALT1 INHIBITORS | Janssen Pharmaceutica NV (BE) | 2026-05-06 | — | — | EP | disclosed |
| WO-2025003414-A1 | MALT1 INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2025-01-02 | — | — | WO | disclosed |
| CN-116323557-A | Cyclobutylamide monoacylglycerol lipase modulators | 詹森药业有限公司 | 2023-06-23 | — | — | CN | disclosed |