Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | PDCD1LG2 | Q9BQ51 | 7/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 7/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | IKBKB | O14920 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | GPR183 | P32249 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.30 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26631319 | 1.00 | DGAT1 (0.37) | DGAT1POLBTDP1LRRK2PDCD1LG2 | |
| SCHEMBL29497388 | 0.86 | DGAT1 (0.46) | DGAT1GPR183ACACBGPR119 | |
| SCHEMBL29024808 | 0.86 | DGAT1 (0.46) | DGAT1GPR183ACACBGPR119 | |
| SCHEMBL25411527 | 0.86 | CD274 (0.34) | POLBTDP1PDCD1LG2CD274HCRTR1 | |
| SCHEMBL30503611 | 0.86 | CD274 (0.34) | POLBTDP1PDCD1LG2CD274HCRTR1 | |
| SCHEMBL25413318 | 0.84 | DGAT1 (0.35) | DGAT1POLBTDP1PDCD1LG2CD274 | |
| SCHEMBL25411360 | 0.81 | DGAT1 (0.32) | DGAT1IKBKBACACB | |
| SCHEMBL30503535 | 0.81 | DGAT1 (0.32) | DGAT1IKBKBACACB | |
| SCHEMBL29427092 | 0.81 | DGAT1 (0.42) | DGAT1ACACBGPR119 | |
| SCHEMBL26631355 | 0.78 | FFAR4 (0.32) | DGAT1ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116323557-A | Cyclobutylamide monoacylglycerol lipase modulators | 詹森药业有限公司 | 2023-06-23 | — | — | CN | disclosed |