Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.39 |
| ▸ | PDE4A | P27815 | 2/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.36 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.36 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.36 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.36 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.36 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29497388 | 1.00 | DGAT1 (0.46) | DGAT1GPR119PDE4BPDE4APDE4C | |
| SCHEMBL29427092 | 0.94 | DGAT1 (0.42) | DGAT1GPR119PDE4BPDE4APDE4C | |
| SCHEMBL29427128 | 0.87 | GPR119 (0.42) | DGAT1GPR119PDE4BPDE4APDE4C | |
| SCHEMBL26631490 | 0.87 | GPR119 (0.42) | DGAT1GPR119PDE4BPDE4APDE4C | |
| SCHEMBL26631319 | 0.86 | DGAT1 (0.37) | DGAT1GPR119ACACBGPR183 | |
| SCHEMBL30503541 | 0.86 | DGAT1 (0.37) | DGAT1GPR119ACACBGPR183 | |
| SCHEMBL26631417 | 0.86 | GPR119 (0.41) | DGAT1GPR119PDE4BPDE4APDE4C | |
| SCHEMBL26631467 | 0.84 | DGAT1 (0.43) | DGAT1GPR119PDE4BPDE4APDE4C | |
| SCHEMBL29427009 | 0.84 | DGAT1 (0.43) | DGAT1GPR119PDE4BPDE4APDE4C | |
| SCHEMBL25411482 | 0.81 | GPR119 (0.42) | DGAT1GPR119PDE4BPDE4APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116323557-A | Cyclobutylamide monoacylglycerol lipase modulators | 詹森药业有限公司 | 2023-06-23 | — | — | CN | disclosed |