Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | CDK7 | P50613 | 1/20 | 0.30 |
| ▸ | CCNH | P51946 | 1/20 | 0.30 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30503618 | 0.80 | LRRK2 (0.47) | LRRK2SCN9AHSD11B1AR | |
| SCHEMBL30224284 | 0.80 | MAOB (0.30) | MAOB | |
| SCHEMBL23993315 | 0.80 | MAOB (0.30) | MAOB | |
| SCHEMBL30503569 | 0.77 | — | — | |
| SCHEMBL15333670 | 0.75 | — | — | |
| SCHEMBL18538033 | 0.72 | MAT2A (0.36) | LRRK2SCN9A | |
| SCHEMBL23937871 | 0.71 | DYRK1A (0.46) | LRRK2MAOB | |
| SCHEMBL25437806 | 0.70 | LRRK2 (0.36) | LRRK2HSD11B1 | |
| SCHEMBL12127453 | 0.69 | OPRM1 (0.44) | — | |
| SCHEMBL31403719 | 0.69 | LRRK2 (0.43) | LRRK2HTTMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116323557-A | Cyclobutylamide monoacylglycerol lipase modulators | 詹森药业有限公司 | 2023-06-23 | — | — | CN | disclosed |