Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.40 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23358163 | 0.86 | SCN9A (0.43) | ALDH1A1MAPTATMSLC22A12ADRA2A | |
| SCHEMBL13334872 | 0.84 | LRRK2 (0.41) | ALOX5APFEN1SLC13A5 | |
| SCHEMBL30783187 | 0.81 | DHODH (0.42) | SLC22A12NFE2L2 | |
| SCHEMBL4623062 | 0.80 | FPR2 (0.46) | SLC22A12NFE2L2 | |
| SCHEMBL322870 | 0.79 | SLC22A12 (0.55) | ALDH1A1MAPTATMSLC22A12NFE2L2 | |
| SCHEMBL30440802 | 0.79 | SLC22A12 (0.55) | ALDH1A1MAPTATMSLC22A12NFE2L2 | |
| SCHEMBL18997797 | 0.77 | SSTR4 (0.48) | SLC22A12 | |
| SCHEMBL10203045 | 0.77 | SCN9A (0.37) | ALDH1A1MAPTATMSLC22A12ADRA2A | |
| SCHEMBL28505112 | 0.77 | FPR2 (0.42) | SLC22A12NFE2L2 | |
| SCHEMBL10202983 | 0.77 | SCN9A (0.37) | ALDH1A1MAPTATMSLC22A12ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116323557-A | Cyclobutylamide monoacylglycerol lipase modulators | 詹森药业有限公司 | 2023-06-23 | — | — | CN | disclosed |