Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.55 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | APLNR | P35414 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL322870 | 1.00 | SLC22A12 (0.55) | SLC22A12NFE2L2ALDH1A1MAPTATM | |
| SCHEMBL25407823 | 0.86 | SLC22A12 (0.47) | SLC22A12NFE2L2ALDH1A1MAPTATM | |
| SCHEMBL77689 | 0.82 | SLC22A12 (0.46) | SLC22A12NFE2L2APLNR | |
| SCHEMBL2387153 | 0.81 | SLC22A12 (0.46) | SLC22A12NFE2L2ALDH1A1MAPTATM | |
| SCHEMBL8989529 | 0.80 | ALDH1A1 (0.46) | SLC22A12NFE2L2ALDH1A1MAPTATM | |
| SCHEMBL30503590 | 0.79 | ALDH1A1 (0.43) | SLC22A12NFE2L2ALDH1A1MAPTATM | |
| SCHEMBL11972428 | 0.78 | APLNR (0.46) | SLC22A12NFE2L2APLNR | |
| SCHEMBL15677613 | 0.78 | SLC22A12 (0.44) | SLC22A12NFE2L2ALDH1A1MAPTATM | |
| SCHEMBL25023658 | 0.78 | SLC22A12 (0.44) | SLC22A12NFE2L2APLNR | |
| SCHEMBL19002316 | 0.78 | SSTR4 (0.51) | SLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112625028-B | Compounds and compositions for inhibiting SHP2 activity | 诺华股份有限公司 | 2024-10-29 | — | — | CN | disclosed |
| CN-110845490-B | 2-acylaminothiazole derivative or salt thereof | 旭飞药业股份有限公司 | 2023-03-28 | — | — | CN | disclosed |