Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL169128 | 1.00 | MAPT (0.53) | MAPTHTTMEN1KMT2ANPSR1 | |
| SCHEMBL4049684 | 0.84 | AR (0.57) | MAPTHTTMEN1KMT2ANPSR1 | |
| SCHEMBL1042555 | 0.82 | NOTUM (0.49) | MAPTHTTMEN1KMT2ANPSR1 | |
| SCHEMBL29616577 | 0.82 | NOTUM (0.49) | MAPTHTTMEN1KMT2ANPSR1 | |
| SCHEMBL16355402 | 0.79 | ALDH1A1 (0.44) | MAPTHTTMEN1KMT2ANPSR1 | |
| SCHEMBL4273522 | 0.78 | SMN1; SMN2 (0.45) | SMN1; SMN2NOTUMSYKARKIF11 | |
| SCHEMBL31373428 | 0.76 | KDM1A (0.48) | MAPTHTTMEN1KMT2ANPSR1 | |
| SCHEMBL10030392 | 0.76 | GLA (0.54) | SMN1; SMN2SYKARPDE3BPDE3A | |
| SCHEMBL84053 | 0.76 | SMN1; SMN2 (0.44) | SMN1; SMN2NOTUMSYKARTAS2R14 | |
| SCHEMBL31373429 | 0.76 | KDM1A (0.48) | MAPTHTTMEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3573972-B1 | RORGAMMA MODULATORS AND USES THEREOF | GENFIT (FR) | 2026-01-14 | — | — | EP | disclosed |
| CN-111170991-B | Antiproliferative compounds and methods of synthesis thereof | 细胞基因公司 | 2023-10-31 | — | — | CN | disclosed |
| CN-116323557-A | Cyclobutylamide monoacylglycerol lipase modulators | 詹森药业有限公司 | 2023-06-23 | — | — | CN | disclosed |