Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABAT | P80404 | 1/20 | 0.43 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | OAT | P04181 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL25404022 | 0.98 | ABAT (0.42) | ABATGABRR1TSHRMAPK1HSD17B10 | |
| SCHEMBL23706926 | 0.75 | ABAT (0.47) | ABATGABRR1TSHRMAPK1HSD17B10 | |
| Hydrochloric Acid SCHEMBL25403649 | 0.74 | ABAT (0.43) | ABATGABRR1TSHRMAPK1HSD17B10 | |
| Hydrochloric Acid SCHEMBL23699861 | 0.73 | ABAT (0.46) | ABATGABRR1TSHRMAPK1HSD17B10 | |
| SCHEMBL23706934 | 0.71 | GABRR1 (0.44) | ABATGABRR1TSHRMAPK1HSD17B10 | |
| SCHEMBL23706930 | 0.71 | ABAT (0.47) | ABATGABRR1TSHRMAPK1HSD17B10 | |
| Hydrochloric Acid SCHEMBL23699851 | 0.69 | THRB (0.43) | ABATGABRR1TSHRMAPK1HSD17B10 | |
| Hydrochloric Acid SCHEMBL23699848 | 0.69 | ABAT (0.46) | ABATGABRR1TSHRMAPK1HSD17B10 | |
| SCHEMBL4315702 | 0.69 | GABRR1 (0.42) | ABATGABRR1TSHRMAPK1HSD17B10 | |
| Hydrochloric Acid SCHEMBL25404353 | 0.69 | ABAT (0.42) | ABATGABRR1TSHRMAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4482478-A4 | (3S,4R)-3-AMINO-4-(DIFLUOROMETHYL)CYCLOPENT-1-ENE-1-CARBOXYLIC ACID AND RELATED COMPOUNDS AS SELECTIVE INACTIVATORS OF ORNITHINE AMINOTRANSFERASE | UNIV NORTHWESTERN (US) | 2026-03-04 | — | — | EP | disclosed |
| US-20250171397-A1 | (3S,4R)-3-AMINO-4-(DIFLUOROMETHYL)CYCLOPENT-1-ENE-1-CARBOXYLIC ACID AND RELATED COMPOUNDS AS SELECTIVE INACTIVATORS OF ORNITHINE AMINOTRANSFERASE | UNIV NORTHWESTERN (US) | 2025-05-29 | — | — | US | disclosed |
| EP-4482478-A2 | (3S,4R)-3-AMINO-4-(DIFLUOROMETHYL)CYCLOPENT-1-ENE-1-CARBOXYLIC ACID AND RELATED COMPOUNDS AS SELECTIVE INACTIVATORS OF ORNITHINE AMINOTRANSFERASE | Northwestern University (US) | 2025-01-01 | — | — | EP | disclosed |
| EP-4482478-A2 | (3S,4R)-3-AMINO-4-(DIFLUOROMETHYL)CYCLOPENT-1-ENE-1-CARBOXYLIC ACID AND RELATED COMPOUNDS AS SELECTIVE INACTIVATORS OF ORNITHINE AMINOTRANSFERASE | Northwestern University (US) | 2025-01-01 | — | — | EP | disclosed |
| WO-2024196853-A1 | SUBSTITUTED CYCLOHEXENE AND CYCLOHEXANE INHIBITORS OF ORNITHINE AMINOTRANSFERASE | NORTHWESTERN UNIVERSITY (US) | 2024-09-26 | — | — | WO | disclosed |
| WO-2023164715-A3 | (3S,4R)-3-AMINO-4-(DIFLUOROMETHYL)CYCLOPENT-1-ENE-1-CARBOXYLIC ACID AND RELATED COMPOUNDS AS SELECTIVE INACTIVATORS OF ORNITHINE AMINOTRANSFERASE | NORTHWESTERN UNIVERSITY (US) | 2023-10-05 | — | — | WO | disclosed |
| WO-2023164715-A2 | (3S,4R)-3-AMINO-4-(DIFLUOROMETHYL)CYCLOPENT-1-ENE-1-CARBOXYLIC ACID AND RELATED COMPOUNDS AS SELECTIVE INACTIVATORS OF ORNITHINE AMINOTRANSFERASE | NORTHWESTERN UNIVERSITY (US) | 2023-08-31 | — | — | WO | disclosed |
| WO-2023164715-A2 | (3S,4R)-3-AMINO-4-(DIFLUOROMETHYL)CYCLOPENT-1-ENE-1-CARBOXYLIC ACID AND RELATED COMPOUNDS AS SELECTIVE INACTIVATORS OF ORNITHINE AMINOTRANSFERASE | NORTHWESTERN UNIVERSITY (US) | 2023-08-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250171397-A1 | (3S,4R)-3-AMINO-4-(DIFLUOROMETHYL)CYCLOPENT-1-ENE-1-CARBOXYLIC ACID AND RELATED COMPOUNDS AS SELECTIVE INACTIVATORS OF ORNITHINE AMINOTRANSFERASE | DLAT, HHAT, OAT | ABAT 6/4885GABRR1 2226/4885TSHR 1835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.