Benzophenone

Benzophenone

SCHEMBL30504146

O=C(c1ccccc1)c1ccccc1.c1ccc2nc3ccccc3cc2c1

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.62
HPGD P15428 3/20 0.62
MAPT P10636 2/20 0.62
GLA P06280 1/20 0.62
ACHE P22303 1/20 0.62
CNR2 P34972 2/20 0.61
ATM Q13315 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
MEN1 O00255 4/20 0.52
KMT2A Q03164 4/20 0.52
MGAM O43451 2/20 0.52
SRD5A2 P31213 1/20 0.50
POLB P06746 2/20 0.49
KDM4E B2RXH2 2/20 0.49
LMNA P02545 1/20 0.49
GAA P10253 1/20 0.49
MAPK1 P28482 1/20 0.49
RECQL P46063 1/20 0.49
GFER P55789 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzil SCHEMBL9476443 0.88 ALDH1A1 (0.62) ALDH1A1HPGDMAPTGLAACHE
Acridine SCHEMBL9644821 0.88 ALDH1A1 (0.62) ALDH1A1HPGDMAPTGLAACHE
Acridine SCHEMBL6424894 0.85 HTR3A (0.59) ALDH1A1HPGDMAPTGLAACHE
Benzophenone SCHEMBL2577611 0.84 ALDH1A1 (0.74) ALDH1A1HPGDMAPTATMTDP1
SCHEMBL27739759 0.84 ALDH1A1 (0.58) ALDH1A1HPGDMAPTGLAACHE
Acridine SCHEMBL29143509 0.83 ALDH1A1 (0.62) ALDH1A1HPGDMAPTGLAACHE
Acridine SCHEMBL4854060 0.83 ALDH1A1 (0.68) ALDH1A1HPGDMAPTGLAACHE
Acridine SCHEMBL8643076 0.83 ALDH1A1 (0.68) ALDH1A1HPGDMAPTGLAACHE
Acridine SCHEMBL11500721 0.83 MAPT (0.68) ALDH1A1HPGDMAPTGLAACHE
SCHEMBL11022121 0.82 CNR2 (0.51) ALDH1A1HPGDMAPTGLAACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115611692-B Method for synthesizing fluorine-containing compound 凯莱英生命科学技术(天津)有限公司 2023-05-12 CN disclosed