Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 4/20 | 0.60 |
| ▸ | CES1 | P23141 | 12/20 | 0.46 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.43 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 2/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | CASP2 | P42575 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.34 |
| ▸ | LIG1 | P18858 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4585146 | 1.00 | TGM2 (0.60) | TGM2CES1DNMT1ALDH1A1ALDH2 | |
| SCHEMBL16647154 | 0.82 | TGM2 (0.55) | TGM2CES1DNMT1ALDH1A1ALDH2 | |
| SCHEMBL25365915 | 0.78 | TGM2 (0.50) | TGM2CES1DNMT1ALDH1A1ALDH2 | |
| SCHEMBL29493880 | 0.78 | TGM2 (0.50) | TGM2CES1DNMT1ALDH1A1ALDH2 | |
| SCHEMBL30288310 | 0.75 | TGM2 (1.00) | TGM2CES1DNMT1ALDH1A1ALDH2 | |
| SCHEMBL4586483 | 0.75 | TGM2 (1.00) | TGM2CES1DNMT1ALDH1A1ALDH2 | |
| SCHEMBL31113465 | 0.75 | TGM2 (0.50) | TGM2CES1DNMT1ALDH1A1ALDH2 | |
| SCHEMBL3359736 | 0.75 | TGM2 (0.50) | TGM2CES1DNMT1ALDH1A1ALDH2 | |
| SCHEMBL29860116 | 0.75 | CES1 (0.50) | TGM2CES1DNMT1ALDH1A1ALDH2 | |
| SCHEMBL3076875 | 0.75 | CES1 (0.50) | TGM2CES1DNMT1ALDH1A1ALDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119330941-A | Antitumor compounds as UPR agonists and uses thereof | 南京圣和药业股份有限公司 | 2025-01-21 | — | — | CN | disclosed |
| CN-116535619-A | Preparation method and application of high molecular weight arylene isatin polymer and ionic solvent film | 宁波中科氢易膜科技有限公司 | 2023-08-04 | — | — | CN | disclosed |