Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 8/20 | 0.47 |
| ▸ | ATR | Q13535 | 1/20 | 0.47 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | VCP | P55072 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3292931 | 1.00 | PRKCI (0.47) | PRKCIATRGRM5TLR7PDE3B | |
| SCHEMBL277948 | 0.84 | PDE3B (0.45) | PRKCIPDE3BPDE3AKDM4ENPC1 | |
| SCHEMBL27669301 | 0.80 | PRKCI (0.50) | PRKCIATRGRM5TLR7VCP | |
| SCHEMBL29578557 | 0.78 | ATR (0.53) | PRKCIATRGRM5TLR7KDM4E | |
| SCHEMBL13544700 | 0.78 | ADORA3 (0.41) | PRKCIPDE3BPDE3AKDM4EALDH1A1 | |
| SCHEMBL1097431 | 0.78 | PRKCI (0.48) | PRKCIATRGRM5TLR7ALDH1A1 | |
| SCHEMBL65106 | 0.78 | ATR (0.53) | PRKCIATRGRM5TLR7KDM4E | |
| SCHEMBL20853598 | 0.78 | PRKCI (0.48) | PRKCIATRGRM5TLR7VCP | |
| SCHEMBL30065824 | 0.78 | PRKCI (0.48) | PRKCIATRGRM5TLR7ALDH1A1 | |
| SCHEMBL13697278 | 0.78 | PDE3B (0.39) | PRKCIATRGRM5PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111892601-B | Pyridopyrazolocinnoline compound and preparation method and application thereof | 陕西大美化工科技有限公司 | 2023-09-26 | — | — | CN | claimed |
| CN-111892597-B | Quinoxalinyl pyridopyrazine compound and preparation method and application thereof | 山西天宏达安医药科技有限公司 | 2023-07-25 | — | — | CN | claimed |
| CN-111925370-B | Pyrazinopyrazoles naphthyridine compound and preparation method and application thereof | 湖北科苑生物药业有限公司 | 2023-07-21 | — | — | CN | claimed |
| EP-4587014-A2 | C5AR1 ANTAGONISTS AND USES THEREOF | Vanqua Bio, Inc. (US) | 2025-07-23 | — | — | EP | disclosed |
| WO-2024259169-A1 | PYRIMIDINE BASED MODULATORS AND USES THEREOF | QUANTA THERAPEUTICS, INC. (US) | 2024-12-19 | — | — | WO | disclosed |
| WO-2024059096-A2 | C5AR1 ANTAGONISTS AND USES THEREOF | VANQUA BIO, INC. (US) | 2024-03-21 | — | — | WO | disclosed |
| CN-111892601-B | Pyridopyrazolocinnoline compound and preparation method and application thereof | 陕西大美化工科技有限公司 | 2023-09-26 | — | — | CN | disclosed |
| CN-111925370-B | Pyrazinopyrazoles naphthyridine compound and preparation method and application thereof | 湖北科苑生物药业有限公司 | 2023-07-21 | — | — | CN | disclosed |