Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.62 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 11/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 10/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27618417 | 0.89 | BRD4 (0.53) | BRD4PAX8HSD17B2HSD17B1CREBBP | |
| SCHEMBL24394975 | 0.84 | BRD4 (0.63) | BRD4PAX8HSD17B2HSD17B1CREBBP | |
| SCHEMBL10210873 | 0.84 | BRD4 (0.52) | BRD4PAX8HSD17B2HSD17B1 | |
| SCHEMBL1317250 | 0.83 | BRD4 (0.50) | BRD4PAX8HSD17B2HSD17B1CREBBP | |
| SCHEMBL14909476 | 0.83 | BRD4 (0.50) | BRD4PAX8HSD17B2HSD17B1CREBBP | |
| SCHEMBL3910121 | 0.83 | BRD4 (0.51) | BRD4PAX8HSD17B2HSD17B1CREBBP | |
| SCHEMBL67115 | 0.83 | BRD4 (0.51) | BRD4PAX8CREBBPMEN1RAB9A | |
| SCHEMBL30013638 | 0.83 | BRD4 (0.51) | BRD4PAX8CREBBPMEN1RAB9A | |
| SCHEMBL14065550 | 0.83 | BRD4 (0.51) | BRD4PAX8HSD17B2HSD17B1CREBBP | |
| SCHEMBL30455057 | 0.83 | HTR3E (0.51) | BRD4PAX8HSD17B2HSD17B1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116490507-A | Heterocyclic condensation CDC7 kinase inhibitors for the treatment of cancer | 薛定谔公司 | 2023-07-25 | — | — | CN | disclosed |