Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.51 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL67115 | 1.00 | BRD4 (0.51) | BRD4PAX8RIPK1KMT2AMEN1 | |
| SCHEMBL29971432 | 0.83 | BRD4 (0.40) | BRD4PAX8KMT2AMEN1NPSR1 | |
| SCHEMBL10210873 | 0.83 | BRD4 (0.52) | BRD4PAX8LMNAKDM4ESMN1; SMN2 | |
| SCHEMBL30504285 | 0.83 | BRD4 (0.62) | BRD4PAX8KMT2AMEN1NPSR1 | |
| SCHEMBL2377323 | 0.82 | MTNR1A (0.40) | BRD4RIPK1KMT2AMEN1MTNR1A | |
| SCHEMBL3910121 | 0.81 | BRD4 (0.51) | BRD4PAX8KMT2AMEN1NPSR1 | |
| SCHEMBL14065550 | 0.81 | BRD4 (0.51) | BRD4PAX8KMT2AMEN1NPSR1 | |
| SCHEMBL29004748 | 0.81 | HTR3E (0.51) | BRD4PAX8RIPK1KMT2ANPSR1 | |
| SCHEMBL30455057 | 0.81 | HTR3E (0.51) | BRD4PAX8RIPK1KMT2ANPSR1 | |
| SCHEMBL27450194 | 0.81 | BRD4 (0.51) | BRD4PAX8KMT2AMEN1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116635029-A | REV-ERB agonists | 圣路易斯大学 | 2023-08-22 | — | — | CN | disclosed |
| CN-115362003-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2022-11-18 | — | — | CN | disclosed |