Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | PARP1 | P09874 | 2/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HBB | P68871 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25201307 | 1.00 | KDM4E (0.47) | KDM4EALDH1A1SMN1; SMN2HPGDCA12 | |
| SCHEMBL2731858 | 0.93 | ALDH1A1 (0.47) | KDM4EALDH1A1SMN1; SMN2HPGDCA12 | |
| SCHEMBL29909400 | 0.93 | ALDH1A1 (0.47) | KDM4EALDH1A1SMN1; SMN2HPGDCA12 | |
| SCHEMBL3426314 | 0.84 | KDM4E (0.53) | KDM4EALDH1A1SMN1; SMN2HPGDCA12 | |
| SCHEMBL7034913 | 0.84 | KDM4E (0.53) | KDM4EALDH1A1SMN1; SMN2HPGDCA12 | |
| SCHEMBL31748445 | 0.82 | MAPT (0.42) | KDM4EALDH1A1SMN1; SMN2IDO1LMNA | |
| SCHEMBL22725084 | 0.82 | MAPT (0.42) | KDM4EALDH1A1SMN1; SMN2IDO1LMNA | |
| SCHEMBL3668179 | 0.78 | KDM4E (0.47) | KDM4EALDH1A1SMN1; SMN2HPGDCA12 | |
| SCHEMBL13814616 | 0.78 | KDM4E (0.47) | KDM4EALDH1A1SMN1; SMN2HPGDCA12 | |
| SCHEMBL13804376 | 0.74 | KDM4E (0.51) | KDM4EALDH1A1SMN1; SMN2HPGDCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118302418-B | Aromatic heterocyclic compound and application thereof | 中国科学院上海药物研究所 | 2025-05-02 | — | — | CN | disclosed |
| US-20250042862-A1 | AROMATIC HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2025-02-06 | — | — | US | disclosed |
| CN-118302418-A | Aromatic heterocyclic compound and application thereof | 中国科学院上海药物研究所 | 2024-07-05 | — | — | CN | disclosed |
| CN-116102533-A | Aromatic heterocyclic compound and application thereof | 中国科学院上海药物研究所 | 2023-05-12 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250042862-A1 | AROMATIC HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | KDM1B, KDM1A, KDM3B | KDM4E 25/4885ALDH1A1 165/4885SMN1; SMN2 4105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.