Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | BLM | P54132 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | GFER | P55789 | 2/20 | 0.48 |
| ▸ | ALPL | P05186 | 2/20 | 0.48 |
| ▸ | ALPI | P09923 | 1/20 | 0.48 |
| ▸ | ALPG | P10696 | 1/20 | 0.48 |
| ▸ | NQO2 | P16083 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29403669 | 0.91 | LCK (0.64) | LCKALDH1A1CYP3A4RECQLKDM4E | |
| SCHEMBL170797 | 0.91 | LCK (0.64) | LCKALDH1A1CYP3A4RECQLKDM4E | |
| Formic Acid SCHEMBL29030387 | 0.83 | KDM4E (0.61) | LCKALDH1A1CYP3A4RECQLKDM4E | |
| Ethylene Glycol SCHEMBL7334630 | 0.82 | TRPA1 (0.50) | ALDH1A1CYP3A4RECQLTRPA1PTGS2 | |
| Sulfuric Acid SCHEMBL23249872 | 0.81 | KDM4E (0.54) | LCKALDH1A1CYP3A4KDM4ERAB9A | |
| Acetone SCHEMBL22719872 | 0.81 | IAPP (0.58) | LCKALDH1A1CYP3A4KDM4ERAB9A | |
| Styrene SCHEMBL4416848 | 0.81 | ALDH1A1 (0.58) | LCKALDH1A1CYP3A4KDM4ERAB9A | |
| Acetic Acid SCHEMBL29030379 | 0.79 | IAPP (0.56) | LCKALDH1A1CYP3A4KDM4ERAB9A | |
| Propionic Acid SCHEMBL29030427 | 0.79 | IAPP (0.56) | LCKALDH1A1CYP3A4KDM4ERAB9A | |
| Ethylene Glycol SCHEMBL28139258 | 0.78 | ALDH1A1 (0.69) | ALDH1A1CYP3A4RECQLTRPA1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11106747-A | — | — | None | — | — | JP | disclosed |
| US-7769442-B2 | Device and method for inhibiting release of pro-inflammatory mediator | MEDTRONIC, INC. (US) | 2010-08-03 | — | — | US | disclosed |
| US-7418292-B2 | Device and method for attenuating an immune response | MEDTRONIC, INC. (US) | 2008-08-26 | — | — | US | disclosed |
| US-20060287678-A1 | DEVICE AND METHOD FOR INHIBITING RELEASE OF PRO-INFLAMMATORY MEDIATOR | MEDTRONIC, INC. (US) | 2006-12-21 | — | — | US | disclosed |
| WO-2005032653-A1 | DEVICE AND METHOD FOR ATTENUATING AN IMMUNE RESPONSE | MEDTRONIC, INC (US) | 2005-04-14 | — | — | WO | disclosed |
| US-20050075701-A1 | Device and method for attenuating an immune response | MEDTRONIC, INC. (US) | 2005-04-07 | — | — | US | disclosed |
| US-20050075702-A1 | Device and method for inhibiting release of pro-inflammatory mediator | MEDTRONIC, INC. (US) | 2005-04-07 | — | — | US | disclosed |
| JP-H11106747-A | METHOD FOR DETECTING FLUORESCENCE OF HYDROXYPHENYL COMPOUND | TOSOH CORP | 1999-04-20 | — | — | JP | disclosed |
| EP-0327345-B1 | Hair darkening compositions | BEECHAM GROUP PLC (GB) | 1993-10-20 | — | — | EP | disclosed |
| US-5227472-A | Antigen for producing an antibody against MHPG | DAIICHI RADIOISOTOPE LABORATORIES, LTD. (JP) | 1993-07-13 | — | — | US | disclosed |
| EP-0327345-A2 | Hair darkening compositions | Wella Aktiengesellschaft (DE) | 1989-08-09 | — | — | EP | disclosed |