SCHEMBL31020880

SCHEMBL31020880

CC(C)C[C@H](N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)O)C(C)C

nearest known ligand 0.49

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ NPY1R P25929 1/20 0.49
▸ NPY2R P49146 1/20 0.49
▸ NPY4R P50391 1/20 0.49
▸ REN P00797 2/20 0.47
▸ BACE1 P56817 10/20 0.46
▸ BACE2 Q9Y5Z0 3/20 0.46
▸ FOLH1 Q04609 1/20 0.46
▸ ACE P12821 1/20 0.44
▸ OPRD1 P41143 2/20 0.44
▸ OPRM1 P35372 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31020881 0.93 NPY4R (0.49) NPY1RNPY2RNPY4RBACE1BACE2
SCHEMBL31510665 0.93 BACE1 (0.52) BACE1BACE2
SCHEMBL31513110 0.92 NPY1R (0.52) NPY1RNPY2RNPY4RBACE1BACE2
SCHEMBL29679754 0.90 OPRM1 (0.54) NPY1RNPY2RNPY4RBACE1BACE2
SCHEMBL28101251 0.90 BACE1 (0.42) BACE1BACE2
Trifluoroacetic Acid SCHEMBL31518366 0.89 NPY4R (0.49) NPY1RNPY2RNPY4RBACE1BACE2
SCHEMBL7838083 0.89 BACE1 (0.46) BACE1BACE2
SCHEMBL3863461 0.89 BACE1 (0.46) BACE1BACE2
SCHEMBL7838077 0.89 BACE1 (0.46) BACE1BACE2
SCHEMBL3863451 0.89 BACE1 (0.46) BACE1BACE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240197815-A1 METHODS AND COMPOSITIONS FOR IMPROVING VISUAL FUNCTION IN OCULAR DISEASES AND DISORDERS ONL THERAPEUTICS, INC. 2024-06-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240197815-A1 METHODS AND COMPOSITIONS FOR IMPROVING VISUAL FUNCTION IN OCULAR DISEASES AND DISORDERS PDE6C, UACA, EYA3 NPY1R 1471/4885NPY2R 1277/4885NPY4R 1682/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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