SCHEMBL3050642

SCHEMBL3050642

O=C=Nc1ncccn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2489602 0.76
SCHEMBL10509077 0.72
SCHEMBL11248787 0.71 MAPK1 (0.34)
SCHEMBL708434 0.70
SCHEMBL30384637 0.70
SCHEMBL713341 0.70 CYP3A4 (0.30)
Fluoride SCHEMBL28035044 0.69 ADRA2A (0.45)
Water SCHEMBL28118014 0.69 ADRA2A (0.45)
SCHEMBL9271729 0.69 CYP3A4 (0.32)
SCHEMBL30520123 0.67 CYP3A4 (0.47)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0626958-A1 SULFONYLUREAS AS HERBICIDES CIBA-GEIGY AG (CH) 1994-12-07 EP claimed
EP-0402316-B1 Sulphonylureas CIBA GEIGY AG (CH) 1994-09-14 EP claimed
EP-0582021-B1 Sulfonylureas as herbicides CIBA GEIGY AG (CH) 1994-07-13 EP claimed
EP-0582021-A1 Sulfonylureas as herbicides CIBA-GEIGY AG (CH) 1994-02-09 EP claimed
WO-1993017016-A1 SULFONYLUREAS AS HERBICIDES CIBA-GEIGY AG (CH) 1993-09-02 WO claimed
EP-0432442-A1 ACAT inhibitors WARNER-LAMBERT COMPANY (US) 1991-06-19 EP claimed
JP-11140081-A None JP disclosed
CN-114933587-A Preparation method of trifloxysulfuron sodium salt 江苏省农用激素工程技术研究中心有限公司 2022-08-23 CN disclosed
EP-2264023-B1 METHOD FOR PRODUCING PYRIMIDINE COMPOUND ISHIHARA SANGYO KAISHA (JP) 2014-12-17 EP disclosed
CN-104185469-A Cosmetic treatment processes and kit OREAL 2014-12-03 CN disclosed
US-8541406-B2 Thiadiazole derivatives for the treatment of neurodegenerative diseases NV REMYND (BE) 2013-09-24 US disclosed
US-20100261707-A9 THIADIAZOLE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES NV REMYND (BE) 2010-10-14 US disclosed
US-20090233911-A2 THIADIAZOLE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES NV REMYND (BE) 2009-09-17 US disclosed
WO-1994003064-A1 SELECTIVE HERBICIDAL COMPOSITION CIBA-GEIGY AG (CH) 1994-02-17 WO disclosed
EP-0582021-A1 Sulfonylureas as herbicides CIBA-GEIGY AG (CH) 1994-02-09 EP disclosed
WO-1993017016-A1 SULFONYLUREAS AS HERBICIDES CIBA-GEIGY AG (CH) 1993-09-02 WO disclosed
EP-0432442-A1 ACAT inhibitors WARNER-LAMBERT COMPANY (US) 1991-06-19 EP disclosed
US-4668788-A 5,5-dichloro-4,5-dihydro-6-hydroxy-2-trichloromethylpyrimidin-4-one BAYER AKTIENGESELLSCHAFT (DE) 1987-05-26 US disclosed
EP-0173191-A2 5,5-Dichloro-4,5-dihydro-6-hydroxy-2-trichloromethyl-pyrimidin-4-on, process for its preparation and its use BAYER AG (DE) 1986-03-05 EP disclosed
US-4125724-A OF AN ISOCYANATE TO A FORMAMIDO, PLATINUM OR PALLADIUM CATALYST BRISTOL-MYERS COMPANY (US) 1978-11-14 US disclosed